New Mexico vs Oklahoma Picks and Prediction for Saturday, September 19, 2026

By: David Anicetti Published 09/16/2026, 12:11 AM ET

The New Mexico Lobos visit the 24th-ranked Oklahoma Sooners on Saturday at Memorial Stadium in Norman, with the opening kickoff scheduled for 7:30 PM ET on ESPN2. New Mexico is 2-0 overall and 0-0 in the Mountain West after beating the Mercer Bears 70-7, following a 38-7 victory over the Central Michigan Chippewas. Oklahoma is 1-1 overall and 0-0 in the SEC after a 17-10 road loss to the Michigan Wolverines, which followed a 51-0 victory over the UTEP Miners. Be a big winner with our free NCAAF picks.

New Mexico Lobos

New Mexico has scored 108 points through two games while averaging 166 passing yards and 246 rushing yards per game. Luke Moga has completed 17 of 26 passes for 198 yards, three touchdowns, and no interceptions, while Toa Fa'avae has added 134 yards and a touchdown. Scottre Humphrey leads the ground attack with 174 yards and three touchdowns on 28 carries. Kiefer Sibley has added 93 yards, while Cade Keith leads the receiving group with 91 yards and a touchdown.

The Lobos have allowed only seven points per game and have recorded eight sacks and five interceptions. Brett Karhu leads the pass rush with 2.5 sacks, while Clay Martineau and Drew Speech have one each. Mercury Swaim has a team-high 10 tackles, with Martineau adding nine. Tavian Combs, Jaxton Eck, Jahmir Torres, Eric McClain and Xavier Slayton have each recorded an interception.

Injuries: WRs A. Williams and S. Miller and TE Tripp Walsh are questionable with undisclosed injuries, while WR Massiah Mingo (foot) is questionable. QB D. Layne (elbow) and TE J. Olsen (knee) are out.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Oklahoma Sooners

Oklahoma has scored 61 points through two games while averaging 210 passing yards and 135 rushing yards per contest. John Mateer has completed 28 of 50 passes for 414 yards, four touchdowns and one interception. Lloyd Avant leads the rushing attack with 114 yards and a touchdown on 24 carries, while Mateer has added 52 yards. Rocky Beers leads Oklahoma with 137 receiving yards and a touchdown, followed by Trell Harris with 104 yards and a score.

The Sooners have allowed 8.5 points per game, shutting out UTEP before giving up 17 at Michigan. Oklahoma has six sacks but has yet to record an interception. Owen Heinecke leads the defense with 17 tackles, while Taylor Wein has 12 and Reggie Powers III has 11. Wein, Powers, Dane Bathurst, and Adepoju Adebawore each have one sack. Oklahoma has allowed only 17 points through its first two games.

Injuries: LB K. Lewis (undisclosed) and RB Tory Blaylock (hamstring) are questionable.

New Mexico vs Oklahoma Prediction

New Mexico enters with impressive scoring numbers, but Oklahoma represents a major increase in difficulty. The Lobos have relied heavily on a rushing attack averaging 246 yards per game, while their defense has produced eight sacks and five interceptions. Oklahoma’s offense struggled at Michigan, but Mateer has four touchdown passes and several capable targets. The Sooners have allowed only 8.5 points per game and have the defensive front to make New Mexico work harder on the ground. New Mexico’s defense can keep this competitive early, but Oklahoma will create more scoring chances at home. The Lobos will stay inside the large point spread in a lower-scoring game. Final Score Prediction: Oklahoma Sooners win but the New Mexico Lobos will cover, 33-20.

Betting on College Football?

BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Get $350 in Bonus Bets when you wager $5 for 7 days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Get $350 in Bonus Bets when you wager $5 for 7 days ($50 Bonus Bets per day)
Cashable No
DraftKings Sport

New DraftKings Customer: SPEND $5, GET $200 IN BONUSES

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Requirement New DraftKings Customer Offer: SPEND $5, GET $200 IN BONUSES ($50 in Bonus Bets every 7 days for 21 days)*
Cashable No
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview

Best Picks

  • New Mexico Lobos +22.5 (-108)
  • Over 46.5 (-115)
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright Β© 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, Massachusetts, New York, Ontario, or Puerto Rico.