Nicholls State vs Sam Houston Picks and Predictions for Saturday, September 19th, 2026

By: Cameron Ross Published 09/18/2026, 11:47 PM ET

Nicholls State vs Sam Houston Game Information

The Nicholls Colonels will be on the road Saturday for a 7:00 PM matchup inside Elliott T. Bowers Stadium against the Sam Houston Bearkats. Nicholls enters at 2-1 after earning a 3-point victory over UT Rio Grande Valley. Sam Houston is winless following close losses to Troy and Tulsa. Stay in the news with our College Football Picks.

Nicholls State Preview

Ean Rodrigue leads the Nicholls offense this season with 529 yards and 7 touchdowns on 44 completions. Preston Welch has added 65 yards on 5 completions and 32 yards on 6 carries. Tamaj Hoffman leads the Colonels on the ground with 116 yards and 2 touchdowns on 25 attempts. Shane Lee has contributed 90 yards on 29 carries, while Rodrigue has added 81 yards on 29 rushing attempts. Jordan Smith leads Nicholls through the air with 145 yards and 2 touchdowns on 11 catches. Greg Donaldson has recorded 115 yards and 1 score on 4 receptions, while Jackson Dufrene has added 105 yards and 3 touchdowns on 6 grabs.

Sam Houston Preview

Landyn Locke leads Sam Houston with 651 yards and 5 touchdowns on 54 completions. Alton McCaskill is the Bearkats’ leading rusher with 99 yards on 27 carries. Landan Brown has added 48 yards on 12 attempts, while Locke has struggled on the ground with minus-60 yards on 15 carries. Grady O’Neill leads the receiving corps with 148 yards and 1 touchdown on 12 catches. Chris Reed has added 145 yards and 2 scores on 7 receptions, while Jerrian Parker Jr. has produced 101 yards and 1 touchdown on 2 grabs. Tim Burns Jr. has contributed 63 yards on 4 catches.

Nicholls State vs Sam Houston Pick

Sam Houston has been competitive in both losses, but the Bearkats have struggled to establish their running game and protect Locke. Nicholls endured a blowout loss to Kansas State, although the Colonels were much more effective against opponents closer to their level. Rodrigue has thrown 7 touchdowns and should create enough plays to keep this matchup interesting. Sam Houston possesses the stronger roster and should finally earn its first victory, but laying 17.5 points with a team averaging only 19 points per game is difficult to justify. Take Nicholls to remain within the spread behind its passing attack.

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  • Pick: Nicholls +17.5
  • Secondary: Over 49.5

Final Score Prediction: Sam Houston 31, Nicholls 21

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