Northern Iowa vs Wyoming Picks and Predictions for Saturday September 6 2025

By: David Anicetti Published 09/01/2025, 11:07 PM ET

Northern Iowa Preview

The Northern Iowa Panthers visit War Memorial Stadium in Laramie, Wyoming Saturday to play the Wyoming Cowboys. Northern Iowa opened its regular season on Saturday with a 38-14 victory over the Butler Bulldogs. Northern Iowa gained 448 yards of total offense and allowed 336 yards of total offense by Butler, but forced the Bulldogs into three costly turnovers. Be ready for all the action with our free college football picks.

Northern Iowa quarterback Matthew Schecklman has thrown for 214 yards with four touchdowns. Harrison Bey-Buie leads the Panthers in rushing with 81 yards and one touchdown. Tysen Kershaw leads in receiving with 65 yards and one touchdown reception. Linebacker Tucker Langenberg is the leading tackler with 12. Northern Iowa’s defense does not have any sacks, but has made two interceptions

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Wyoming Preview

Wyoming is 1-0 following its 10-0 victory over the Akron Zips last Thursday. The Cowboys gained 426 yards of total offense, including 166 yards rushing and 260 yards passing. The Cowboys held Akron to just 231 yards of total offense. Wyoming led Akron in first downs, third down conversions, and time of possession. However, the Cowboys committed seven penalties to only five by the Zips.

Wyoming quarterback Kaden Anderson has thrown for 260 yards with one touchdown and one interception. Sam Scott is the leading rusher with 132 yards, while the leading receiver is Chris Durr Jr with 190 yards and one touchdown reception. Brayden Johnson leads all tacklers with eight. The Wyoming defense has three sacks and one interception (Brayden Johnson).

Wyoming vs Northern Iowa Pick

Wyoming opened its regular season with a 10-0 victory over the Akron Zips and will add a second straight win at home on Saturday when hosting the Northern Iowa Panthers. Wyoming’s defense held Akron to only 231 yards, and the Cowboys have covered the number in six of their last seven, dating back to last season, while Northern Iowa has covered just three of its last 10. Final Score Prediction: Wyoming Cowboys win and cover ATS 24-7.

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