Ohio State vs Purdue Picks & Predictions for Saturday, November 8, 2025

By: Thomas Pemberton Updated 11/08/2025, 01:41 AM ET

The Ohio State Buckeyes head to Purdue on Saturday to take on the Boilermakers. Kickoff is scheduled for 1:00 PM est at Ross-Ade Stadium. Ohio State is a road -28.5 favorite and the over/under is set at 48.5 points. Don’t bet blind—our free college football predictions show you where the value is.

Ohio State Buckeyes Preview

The Ohio State Buckeyes are the #1 team in the country with a 8-0 record. Ohio State carries a 3-0 road record into Purdue. The Buckeyes rank 1st in the nation allowing 6.9 points against per game. Ohio State beat Penn State in their last game 38-14. QB Julian Sayin threw for 316 yards with 4 touchdowns. Sayin has 23 touchdowns with 3 interceptions on the season. WR Jeremiah Smith leads the team with 725 yards and 9 touchdowns with 55 catches. Bo Jackson leads the Buckeyes on the ground with 538 yards on 81 carries.

Purdue Boilermakers Preview

The Purdue Boilermakers are 2-7 on the season. Purdue is riding a seven game losing streak and carry a 2-3 home field record. The Boilermakers lost to Michigan 21-16 in their last game. QB Ryan Browne threw for 133 yards with a touchdown. Browne has 9 touchdowns and 7 interceptions on the season. Running back Devin Mockobee leads Purdue with 125 carries and 4 touchdowns. Purdue is averaging 22.1 points scored per game.

Ohio State vs Purdue Picks & Prediction

The Ohio State Buckeyes shouldn't have any issues until the last game of the season when they see Michigan. The Buckeyes have UCLA and Rutgers on deck which they will cruise through. Watch for Purdue to be back in this game. Lay the points with the better team on the road. Final Score Prediction: Ohio State Buckeyes win 42-9 and cover ATS.

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Ohio State vs Purdue Best Free Picks

  • Ohio State -28.5
  • OVER 48.5

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