Ohio vs Nebraska Picks and Predictions for Saturday, September 5th, 2026

By: Cameron Ross Published 09/04/2026, 11:17 PM ET

Ohio vs Nebraska Game Information

The Ohio Bobcats will be on the road Saturday afternoon at 12:00 PM inside Memorial Stadium in Lincoln, NE, for a game against the Nebraska Cornhuskers. Ohio had a solid campaign last year, finishing 9-4 overall after winning 6 of its last 7 games, including a 7-point victory over UNLV in the Scooters Coffee Frisco Bowl to end the year. The Nebraska Cornhuskers open the season Saturday looking to improve off last year's struggles. Nebraska was undefeated through their first 3 games and sat at 7-3 overall before finishing the year on a 3-game skid following a 22-point loss to Utah in the SRS Distribution Bowl on New Year’s Eve. Stay in the news with our College Football Picks.

Ohio Preview

Ohio will have a new quarterback under center after Parker Navarro departed the program. Nick Poulos is currently the starter for the Bobcats this year but could split time with Matt Vezza. Poulos completed 4 passes for 19 yards a year ago. Duncan Brune is the top returning ball carrier after recording 585 yards and 8 touchdowns on 120 carries in 2025. Dom Dorwart returns after compiling 119 yards on 11 receptions.Β 

Nebraska Preview

Nebraska also added a new starting quarterback through the transfer portal after Dylan Raiola left the program. Former UNLV quarterback Anthony Colandrea takes over the offense after completing 275 passes for 3,459 yards and 23 touchdowns, and Colandrea ran for 649 yards and 10 scores on 127 carries last year. Mekhi Nelson returns for Nebraska this year, expecting to see his usage increase after 147 yards and 2 scores on 27 carries. Nyziah Hunter led Nebraska a year ago with 617 yards and 5 scores on 43 catches and will return for the Cornhuskers this season.

Ohio vs Nebraska Pick

Nebraska is the stronger team on both sides of the ball and will have a major advantage at home. Ohio could remain competitive early, but the Cornhuskers size and depth should eventually take over the matchup. Look for Nebraska to wear down the Bobcats and pull away with a dominant performance, secure the convincing victory Saturday.

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  • Pick: Nebraska Cornhuskers -23.5
  • Secondary: Over 45.5

Final Score Prediction: Nebraska Cornhuskers win 49-17.

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