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Ole Miss vs Mississippi State Picks & Prediction for Friday, November 28, 2025

By: Thomas Pemberton Published 11/24/2025, 12:50 AM ET

The Mississippi State Bulldogs will host the Ole Miss Rebels on Friday afternoon. Mississippi State is a +7.5 home underdog and the over/under is set at 63.5 points. Kickoff is scheduled for 12:00 PM est at Scott Field. Ole Miss beat Mississippi State 26-14 in their last meeting last season. Stay up to date with our expert's Free College Football Picks. 

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Ole Miss Rebels Preview

The Ole Miss Rebels are 10-1 on the season. The Rebels are riding a four game win streak and they carry a 2-1 road record. Ole Miss is 3rd best in the country averaging 493.8 yards per game. The Rebels beat Florida 34-24 in their last game. QB Trinindad Chambliss threw for 301 yards with a touchdown and an interception in the loss. Chambliss has 14 touchdowns and 3 interceptions on the season. RB Kewan Lacy has been a workhorse for the Rebels. Lacy has 1,136 rushing yards and 19 touchdowns on 231 carries this season. The best sportsbooks are the best way to go when you are betting on Ole Miss.

Mississippi State Bulldogs Preview

The Mississippi State Bulldogs are 5-6 on the season. The Bulldogs have lost two straight games and carry a 3-3 home field record. Mississippi State has allowed more than 40 points in back to back games. The Bulldogs lost to Missouri 49-27 in their last game played.  QB Blake Shapen threw for 199 yards with 2 interceptions in the loss. Shapen has 15 touchdowns and 8 interceptions on the season. WR Brenen Thompson leads the Bulldogs with 868 receiving yards and 6 touchdowns. RB Davon Booth has rushed for 547 yards and 7 touchdowns. Make sure you know about how the fans are looking on prediction markets for Mississippi State with the Onyx Odds promo code.

Ole Miss vs Mississippi State Picks & Prediction

Ole Miss and Mississippi State are two teams heading in different directions. The Rebels are seeking a fifth straight win. While the Bulldogs are in jeopardy of losing their third straight game. Mississippi State is 8-3 against the spread on the season. While Ole Miss is 6-4-1 against the spread. Getting the most out of your bets on Ole Miss vs Mississippi State can be done by using the Fanatics Sportsbook promo code.

  • Final Score Prediction: Ole Miss Rebels win 38-24 and cover ATS.
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Ole Miss vs Mississippi State Best Free Picks

  • Ole Miss Rebels -7.5
  • UNDER 63.5
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