Oregon State vs Oregon Picks and Predictions for Saturday, September 20, 2025
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Oregon State and Oregon meet on Saturday at 3:00 p.m. ET at Autzen Stadium in Eugene. Oregon is 3–0, while Oregon State is 0–3. Although this rivalry is often very close, Oregon has a much stronger team this season compared to Oregon State. Win a big payout in college football with our expert college football picks
Oregon State Preview
Quarterback Maalik Murphy has thrown for 83 yards with 5 touchdowns and a disappointing 6 interceptions on 61.3% passing. The top target is Trent Walker with 23 catches for 302 yards. The run game has been below average, but led by Anthony Hankerson leads with 190 yards on 51 carries and one score, and the Beavers sit at 213 rushing yards on 83 attempts as a team. That puts pressure on the Beavers’ passing game. Oregon State has allowed six sacks and hasn’t generated many big runs on the ground.
On defense, Skyler Thomas leads with 25 tackles, and Jalil Tucker has one of the three interceptions by Oregon State. The Beavers have struggled to give the offense good field position and have recorded just two sacks through three games.
Oregon Preview
Quarterback Dante Moore has been sharp and clean: 50-64 for 657 yards, 7 touchdowns, 1 interception. On the ground, the Ducks have been explosive: 741 rushing yards on 106 carries (7.0 per carry) and 13 rushing TDs, led by Dierre Hill Jr. (161 yards, 2 TD). Malik Benson (161 yards, 2 TD) headlines a wide receiver group that stretches the field and makes the running game even better.
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The defense has played well. Bryce Boettcher leads with 17 tackles, Matayo Uiagalelei has 3 sacks, and Oregon has created takeaways, including two interception return touchdowns in the early going. This is the kind of unit that can get short fields for the offense, resulting in quick scores, especially against an offense such as Oregon State’s.
Oregon State vs Oregon Prediction
Oregon will win by multiple scores. The Ducks have balance and explosive playmakers on both sides. Oregon State needs to take care of the ball and not turn it over, and steady rushing to slow the pace, but Oregon’s passing game and defensive strength will cause the Beavers problems from the start. Final Score Prediction: Oregon Ducks win and cover ATS 49-14.
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Best Pick
- Oregon Ducks -26.5
