Penn State at Michigan State Picks and Predictions for Saturday, November 15, 2025

By: David Anicetti Updated 11/15/2025, 12:17 AM ET
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The Penn State Nittany Lions (3–6, 0–6 Big Ten) visit the Michigan State Spartans (3–6, 0–6 Big Ten) in a Big Ten matchup. Penn State fell 27–24 to Indiana last week, while Michigan State lost 23–20 in overtime at Minnesota on Nov. 1. Both teams are 0–6 in conference play and tied at the bottom of the Big Ten standings. Get the edge this weekend with our free college football picks backed by data and trends.

Penn State vs Michigan State Game Information

Kickoff: 3:30 PM ET, November 15

Where: Spartan Stadium, East Lansing, MI

Penn State Preview

Quarterback Drew Allar has passed for 1,100 yards with eight touchdowns and three interceptions, completing 64.8% of his throws. Devonte Ross leads the receivers with 281 yards and three touchdowns, and Kyron Hudson has 236 yards with two scores. The rushing duo of Kaytron Allen (688 yards, 10 TD) and Nicholas Singleton (292 yards, 7 TD) powers the ground game, and Penn State has 19 rushing touchdowns this season.

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Linebacker Amare Campbell leads the defense with 59 tackles, while Zuriah Fisher has two sacks, and Zakee Wheatley has an interception return of 14 yards. Kicker Ryan Barker is 11 of 12 on field goals with a long of 49 yards and a perfect 28 of 28 on extra points.

Michigan State Preview

Quarterback Aidan Chiles has thrown for 1,392 yards with 10 touchdowns and three interceptions, completing 63.1%. Omari Kelly (529 yards) and Nick Marsh (554 yards, 5 TD) are the top targets. On the ground, Makhi Frazier has 493 yards and two touchdowns, and Chiles has added 227 rushing yards with six scores.

Linebacker Jordan Hall leads the Spartans with 70 tackles, and Malik Spencer has two sacks. Kicker Martin Connington is 9 of 13 on field goals with a long of 50 yards and 19 of 20 on extra points.

Penn State at Michigan State Prediction

Penn State’s rushing with Allen and Singleton gives the visitors a solid ground game. Michigan State can answer with Chiles and Marsh, but Penn State’s running game and red-zone finishing will be the difference on the road in East Lansing. Final Score Prediction: Penn State Nittany Lions win and cover ATS, 28–16.

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Best Picks

  • Penn State Nittany Lions -8.5
  • Under 48.5
  • Kaytron Allen Anytime Touchdown
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