SE Louisiana vs South Alabama Picks and Prediction for Saturday September 5 2026

By: Eddie Kline Published 09/04/2026, 12:16 AM ET

SE Louisiana Preview

Hancock Whitney Stadium will be the scene for a Saturday night college football clash between the SE Louisiana Lions and the South Alabama Jaguars. Make sure you are ready for all the football action with our college football picks. The FCS Lions won seven of eight games in Southland Conference play, but were held to just 25 points combined in their four overall losses. On Thursday, SE Louisiana committed three costly turnovers during a disappointing 34-28 home loss versus Houston Christian.

SE Louisiana rushed the ball 51 times for 248 yards and two scores. Senior QB Kyle Lowe completed 17 of 27 passing attempts for 150 yards and a pair of touchdowns. Lowe added a 55-yard rushing touchdown that trimmed the deficit to 24-14 midway through the third quarter. 

South Alabama Preview

After missing a bowl game for the first time in four seasons, the South Alabama Jaguars are looking to rebound in 2026. The Jaguars (4-8) have been gutted in the transfer portal and head coach Major Applewhite is on the hot seat. South Alabama features an efficient rushing attack, but QB Bishop Davenport (2,073 pass yds, 12 TDs) needs to push the ball downfield more often. Last year, the Jaguars went 0-7 when Davenport failed to complete 71 percent of his passes. 

South Alabama was one of the worst pass rushing teams and hired veteran DC Todd Orlando to provide more havoc.  The Jaguars ranked fourth in the conference in total defense, but gave up north of 30 points per game. LB Tirrell Johnson Jr. made 54 tackles and will look to increase his tackles for loss in the new scheme. 

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SE Louisiana vs South Alabama Pick

SE Louisiana is one of the better FCS programs in the country and has a high-powered offense. The Lions have a game under their belt and have plenty of things to clean up. South Alabama lacks the NIL resources to stay relevant at the FBS level and their transfer losses are problematic. Look for both offenses to shine in a game that goes over the total. Final Score Prediction, South Alabama Jaguars win 35-24.

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