SMU vs Missouri State Picks and Predictions for Saturday, September 13, 2025

By: Cameron Ross Published 09/08/2025, 01:14 AM ET
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SMU vs Missouri State Game Information

The SMU Mustangs will be on the road for the first time this week with a game at Robert W. Plaster Stadium in Springfield, MA, at 3:30 PM against the Missouri State Bears. SMU has one win and one loss on the year, following a three-point double overtime loss to Baylor a week ago. The Missouri State Bears return home this week with one win and one loss on the year, following a one-point victory against Marshall in their last outing. Following a 60-point road loss to USC in week one, for other college football action, see our College Football Picks.

SMU Preview

Kevin Jennings leads the SMU offense this season with 555 yards and five scores on 38 completions. T.J. Harden is the top ball carrier on the team with 157 yards and three touchdowns on 27 carries. Romello Brinson leads the team with 247 yards and three scores on 11 catches. Jalen Cooper has chipped in heavily with 7 catches for 162 yards and two touchdowns.

Missouri State Preview 

Jacob Clark is the offensive leader for Missouri State this season with 506 yards and four scores on 37 completions. Shomari Lawrence leads the team with 99 yards on 29 carries this season. Ramone Green Jr. leads the team with six catches for 151 yards and one touchdown. Jmariyae Robinson has added 115 yards and one score on 6 grabs, while Christian Gardner has chipped in 65 yards and one score on five catches this season.

SMU vs Missouri State Prediction

Despite the loss a week ago, SMU is one of the better teams in the country, and it will get back to its winning ways this week. Look for SMU to dominate this game on both sides of the ball as they do the work against a below-average Missouri State team. Take SMU to pick up their second victory of the season as they get the winning cover on the road this week in Missouri. Final Score Prediction, SMU Mustangs win and cover 49-3.

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