Friday, December 5, 2025

Home / Free Picks / College Football / South Carolina State vs South Carolina Picks and Prediction September 6, 2025

South Carolina State vs South Carolina Picks and Prediction September 6, 2025

By: Jake Allman Published 09/01/2025, 09:31 PM ET

South Carolina State Preview

South Carolina State enters this Week 2 matchup at 1-0 after edging out Wofford 16-15 in the opener. Quarterback William Atkins IV finished 17-of-33 for 175 yards with no touchdowns, and the offense looked inconsistent despite moving the ball in spots. KZ Adams led the backfield with 50 rushing yards on 15 carries, while Jalen Johnson hauled in six catches for 93 yards. The Bulldogs didn’t turn the ball over but failed to convert key red zone chances, settling for field goals and leaving the door open late. South Carolina State may not be your team, but I bet you can find your team with our free college football previews.

The Bulldogs’ defense held Wofford to just 15 points but gave up multiple chunk plays through the air. Linebacker Jordan Franklin recorded seven tackles, and defensive end Mike Lunz added two sacks. While the front seven was able to generate some pressure, coverage breakdowns on third down kept Wofford in the game. That type of performance won’t hold up against an SEC offense with elite athletes and tempo.

Sign Up for Picks And Parlays News Alerts, Get Free Picks and Discounts

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

South Carolina Preview

South Carolina also comes in at 1-0 following a 24-11 win over Virginia Tech in Columbia. LaNorris Sellers threw for 209 yards and a touchdown on just 19 attempts, and looked calm in the pocket while spreading the ball efficiently. Oscar Adaway III led the team with 60 rushing yards on 14 carries, and freshman receiver Nyck Harbor made the biggest splash with three receptions for 99 yards and a score. The offense wasn’t explosive for four quarters, but it finished drives and limited mistakes.

The Gamecocks’ defense was the difference last week, holding Virginia Tech to 11 points and under 300 total yards. Linebacker Fred Johnson paced the unit with 10 tackles, while Jatius Geer brought heat off the edge with a sack. South Carolina was disciplined in its assignments and didn’t allow a single play over 25 yards. The secondary played tight coverage and will have another chance to dominate against a limited Bulldogs passing game.

South Carolina State vs South Carolina Pick

Pick: South Carolina’s defense should force multiple three-and-outs and short fields for Sellers and the offense. With the size mismatch in the trenches and more explosive athletes across the board, the Gamecocks should cover comfortably by halftime. The only real question is how long the starters stay in. South Carolina 45, South Carolina State 10.

BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Bet now
Signup Promo Recommended BetMGM Sport Promo
Min. Deposit $5
Cashable No
Bet365

Bet $5 & Get $150

Show Bonus Code
Bet now
Signup Promo Hot Offer Bet365 Promo
Wagering 1x Bonus
Odds Requirements -500
Cashable Yes
FanDuel Sportsbook

Bet $5 Get $150 in Bonus Bets If Your Bet Wins!

Show Bonus Code
Bet now
Signup Promo Hot Offer FanDuel Sportsbook Promo
Min. Deposit $5
Wagering 1x Deposit
Cashable No
Video: Kennesaw State vs Jacksonville State: CUSA Championship Best Bets | Best College Football Picks
Kennesaw State vs Jacksonville State: CUSA Championship Best Bets | Best College Football Picks
Video: Sun Belt Championship: Troy vs James Madison Best Bets | Best College Football Picks
Sun Belt Championship: Troy vs James Madison Best Bets | Best College Football Picks
Join 250k sports fans & receive free picks
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER (Available in the US) Call 877-8-HOPENY or text HOPENY (467369) (NY) Call 1-800-327-5050 (MA) 21+ only. Please Gamble Responsibly. Call 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). Rewards are non-withdrawable bonus bets that expire in 7 days. In partnership with Kansas Crossing Casino and Hotel. See BetMGM.com for Terms. US promotional offers not available in DC, Mississippi, New York, Nevada, Ontario, or Puerto Rico.