South Carolina vs Florida Picks and Predictions for Saturday October 10 2026

By: Kim Smith Published 10/04/2026, 10:38 PM ET

The South Carolina Gamecocks visit the No. 8 Florida Gators at Ben Hill Griffin Stadium in Gainesville, Florida, on Saturday, October 10, 2026, for an SEC matchup. Kickoff is scheduled for 12:45 PM ET with coverage on SEC Network. South Carolina enters at 2-3 after a heartbreaking 35-34 loss to Kentucky, while Florida is 4-1 after suffering its first defeat in a 45-17 loss at Missouri. Florida is currently favored by approximately 13.5 points, with the total at 58.5. Be sure to check out our free college football picks for more college football predictions throughout the season.

South Carolina Keeps Losing Close Opportunities

South Carolina’s 35-34 loss to Kentucky extended its losing streak to three games and dropped the Gamecocks to 2-3. The frustrating part is that Saturday’s defeat was there for the taking, but South Carolina couldn’t finish the job.

The Gamecocks have generated considerably more offense than their record might suggest, averaging 37.6 points and 491 yards per game. Their ground attack has been particularly productive at 256 rushing yards per contest. Those numbers give South Carolina a realistic opportunity to challenge a Florida defense allowing more production than its national ranking might imply.

Turnovers remain the major concern. South Carolina enters with a negative turnover differential, and giving Florida additional possessions in Gainesville is one of the quickest ways for this matchup to get away from the Gamecocks.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers

Subscribe Now

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Florida Needs a Major Bounce Back

Florida’s 4-0 start came crashing down at Missouri, where the Gators suffered a 45-17 defeat. Florida had previously scored 52 against Ole Miss and 44 at Auburn, so the Missouri result represented a dramatic departure from its earlier offensive production.

The broader numbers remain impressive. Florida is averaging 46.2 points and 491.2 yards per game, including more than 216 rushing yards. The Gators have enough offensive balance to attack South Carolina in several different ways.

The question is whether Florida deserves to lay nearly two touchdowns immediately after getting blown out. Home field helps considerably, and the Gators are 3-0 in Gainesville, but South Carolina’s offensive numbers suggest the Gamecocks are capable of keeping the margin manageable.

South Carolina vs Florida Picks and Predictions

Pick: South Carolina +13.5

South Carolina +13.5 is the side pick. Florida is the better team and should respond strongly after the Missouri loss, but nearly two touchdowns feels excessive against a Gamecocks offense averaging 37.6 points and 491 yards. South Carolina just lost by one to ranked Kentucky and doesn’t need to win here to provide value. Florida’s defense is allowing 27.2 points per game, giving the Gamecocks enough opportunity to remain inside the number.

Pick: Over 58.5

The Over 58.5 is the total pick. Florida has gone Over in four of five games, while its last three contests have produced 83, 80 and 62 combined points. South Carolina’s offense is averaging 37.6 points, but its defense allows 26.8. Both teams are also averaging approximately 491 total yards. Florida should respond offensively after the Missouri loss, and South Carolina has enough firepower to contribute to a game reaching the 60s.

Final Picks: South Carolina +13.5 and Over 58.5

Betting on College Football?

BetMGM Sport

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code
Claim Bonus
Signup Promo Recommended BetMGM Sport Bonus
Min. Deposit $5
Cashable No
FanDuel Sportsbook

New Users – Get $250 in Bonus Bets when you wager $5 for 5 days

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer FanDuel Sportsbook Bonus
Requirement New Users – Get $350 in Bonus Bets when you wager $5 for 7 days ($50 Bonus Bets per day)
Cashable No
DraftKings Sport

New DraftKings Customers: Spend $5+ Get $150 in Bonuses

Show Bonus Code
Claim Bonus
Signup Promo Hot Offer DraftKings Sport Bonus
Min. Deposit $5
Requirement New DraftKings Customers: Spend $5+ Get $150 in Bonuses (Paid Over 14 Days)*
Cashable No
Video: Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions
Video: Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview
logo

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (MI/NJ/PA/WV/WY), 1-800-9-WITH-IT (IN), 1-800-522-4700 (CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA), 1-800-NEXT STEP (AZ), or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ WY). AZ/CO/IL/IN/IA/MI/NJ/PA/TN/VA/WV/WY only. Eligibility restrictions apply. T&C's Apply. Void where prohibited. If you click on a link on this site which takes you to a bookmaker or casino and you subsequently open an account, Pick and Parlays may receive a commission. Bets placed are the responsibility of the bettor.

Copyright © 2026 Picks and Parlays. All rights reserved.

The sports news and information contained at this site is for entertainment purposes only. Any use of this information in violation of laws whether they are federal, state and/or local is prohibited. Picks and Parlays is the nation's premier resource for sports betting and handicapping information.

Sign Up Get $30 Premium Picks Credit + Exclusive Offers
Special Offer
Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win
Play now Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, Massachusetts, New York, Ontario, or Puerto Rico.