South Florida vs. Florida Picks and Prediction September 6 2025

By: Thomas Pemberton Published 09/01/2025, 08:48 PM ET
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Florida Preview

The Florida Gators will play their second straight game at home to open up their season. The 1-0 Florida Gators welcome the 1-0 South Florida Bulls. The Gators beat up on Long Island University in their first game 55-0. Florida played two quarterbacks who each threw 18 passes. They combined for 5 passing touchdowns with no interceptions. Stay up to date with our expert's college football picks. 

Running Back Jordan Baugh led the Gators on the ground. Baugh rushed for 104 yards with a touchdown on just 9 carries. The Florida Gators also had three different wide receivers find the endzone. Florida had 28 first downs in the win while allowing just 2.

South Florida Preview

The South Florida Bulls knocked off #25 Boise State 34-7 in their season opener. The Bulls were led by QB Byrum Brown. Brown threw for 210 yards and rushed for 2 touchdowns. Wideouts Chas Nimrod and Keshaun Singleton each had over 90 receiving yards. The South Florida Bulls allowed the touchdown in the first quarter and didn't allow a point after that.

The Bulls defense caused 5 fumbles and recovered 3 of them. South Florida was outplayed in the first down and total yards battle but that didn't reflect the scoreboard. The Bulls were shutout in the first quarter but scored at least 10 points in the next three. The Florida Gators are a 17 point home favorite this week.

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Florida vs South Florida Pick

The last time these two schools met was back in 2022 when the Gators won by a field goal. Watch for the South Florida Bulls to leave everyone on the field in this game as they hope to knock off a ranked team two weeks in a row. The Gators have more talent and are at home but this one should be a dog fight. Take those free points. Final Score Prediction, Florida Gators win 31-21 but the South Florida Bulls cover ATS.

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