Southern Miss vs Tulane Picks and Predictions for Saturday, September 26th, 2026

By: Cameron Ross Published 09/25/2026, 01:58 PM ET

Southern Miss vs Tulane Game Information

The Southern Miss Golden Eagles return to the road Saturday for a 7:00 PM game in New Orleans, LA, against the Tulane Green Wave. Southern Miss is 1-2 coming into Saturday, riding a 2-game skid after a 28-point home loss to Connecticut. The Tulane Green Wave stay home Saturday at 1-2 following an point road loss to Kansas State last week. Stay in the news with our College Football Picks.

Southern Miss Preview

Ethan Hampton leads Southern Miss this season with 419 yards and 2 touchdowns on 45 completions but has thrown 4 interceptions through 75 attempts. Landry Lyddy has completed 20 passes for 265 yards and 1 score. Steven Robinson leads the Golden Eagles with 246 yards and 4 touchdowns on 56 carries, while Jamarice Wilder has added 120 yards and 2 scores on 23 attempts. Mario Sanders leads the receiving corps with 233 yards and 1 touchdown on 16 catches. MJ Johnson has contributed 103 yards on 7 receptions.

Tulane Preview

Kadin Semonza leads Tulane this season with 517 yards and 2 touchdowns on 38 completions without throwing an interception. Zeon Chriss-Gremillion has added 64 yards on 6 completions. Jaylin Lucas leads the Green Wave with 215 yards and 1 touchdown on only 18 carries, while Johnnie Daniels has contributed 98 yards and 2 scores on 24 attempts. Destyn Hill leads the receiving attack with 158 yards and 1 touchdown on 9 catches. Bredell Richardson has added 82 yards on 6 receptions.

Southern Miss vs Tulane Pick

Southern Miss has struggled with turnovers and enters after allowing 48 points against UConn. Those defensive problems should create favorable opportunities for a Tulane offense looking to respond after losing at Kansas State. The Green Wave can establish Lucas early and use the running game to create manageable passing situations for Semonza. Southern Miss may generate some production through Robinson and Sanders, but consistently finishing drives will be difficult. Look for Tulane to take control before halftime and pull away during the final 2 quarters. The Green Wave should cover the large spread, while Southern Miss can contribute enough points to push the matchup over.

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  • Pick: Tulane Green Wave -18.5
  • Secondary: Over 52.5

Final Score Prediction: Tulane Green Wave win and cover 38-17.

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