Stanford vs SMU Picks and Prediction for Saturday, October 11, 2025

By: Cameron Ross Updated 10/10/2025, 10:51 PM ET
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Stanford vs SMU Information

Gerald J Ford Stadium in Dallas, TX, will welcome the Stanford Cardinal this week for an ACC matchup against the SMU Mustangs at 12:00 PM. Stanford has two wins and three losses on the year after a one-point victory against San Jose State a few weeks ago. The SMU Mustangs stay on their home field this week with three wins and two losses overall after a 13-point home win against Syracuse last week. Maximize your wagers by reading our free college football picks before kickoff.

Stanford Preview

Offensively, Stanford has been up and down this season, with just 20.6 points per game overall. Defensively, Stanford has had their issues, allowing 29.4 points per game this season. Ben Gulbranson leads the Stanford offense this season with 1167 yards and five scores on 94 completions. Michael Ford is the top ball carrier with 347 yards and three touchdowns on 75 carries. Bryce Farrell has been the top receiver on the team with 18 catches for 346 yards and one touchdown.

SMU Preview

The SMU offense has carried the team this season, scoring an average of 34 points per game through its first five games. Defensively, SMU has done the job, holding opponents to an average of 24.8 points per game overall; however, they have given up an average of 41.5 points per game during their two losses. Kevin Jennings leads the SMU offense this season with 1411 yards and 13 scores on 115 completions. T.J. Harden is the top running back on the team, with 376 yards and five touchdowns on 73 carries. Romello Brinson has led the way with 26 catches for 436 yards and three touchdowns this year.

Stanford vs SMU Prediction

Both teams have had their issues coming into this matchup, but SMU will do the work. The Mustangs are strong on the offensive side and will thrive in front of their home crowd this week. Take SMU to stay undefeated in conference as they get the win and cover at home against a below-average Stanford team. Final Score Prediction, SMU Mustangs win and cover 35-14.

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Best Picks:

  • SMU Mustangs -17.5
  • Under 55.5
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