Troy vs Clemson Picks and Prediction for Saturday, September 6, 2025

By: Cameron Ross Published 09/02/2025, 11:54 PM ET

Troy Preview

The Troy Trojans will be on the road for the first time this week with a game in Clemson against the Clemson Tigers. Troy is undefeated this season following an 18-point victory in game one of the year. Offensively, Troy was the better team in their week 1 matchup, scoring 38 points, including 28 in the fourth quarter, on 416 total yards. Defensively, Troy was mediocre, giving up 20 points on 249 yards, but allowed just four third-down conversions and forced 1 turnover in the win. For other college basketball action, see our College Football Picks.

Deuce Hogan led the way for the Troy offense in week 1, completing 21 passes for 184 yards and one score. Tamaj Hoffman led the way on the ground for the Trojans with 52 yards on 9 carries. Miequle Brock Jr. added a team-high 87 yards and one touchdown on 6 receptions. Scrappy Osby added 36 yards on five receptions in the game.

Clemson Preview

The Clemson Tigers come into Week 2 winless on the season following a 7-point loss against LSU. Clemson was ranked #4 in the preseason poll, but has lost three of the last four overall, dating back to last season. Offensively, Clemson was below their standard in week 1, scoring just 10 points, including none in the second half, with 261 total yards. Defensively, Clemson was outmatched, giving up 354 yards and 17 points after LSU scored 14 points in the second half.

Cade Klubnik had a below-average season debut, completing just 19 passes for 230 yards in the game. Adam Randall led the way on the ground for Clemson with 16 yards and one score on five carries. Bryant Wesco Jr led the team with 66 yards on 4 receptions. TJ Moore chipped in four catches for 55 yards in the game.

Subscribe Now

I authorize Picks And Parlays to send me promotional emails

I understand that I can unsubscribe at any time. I have read and accepted the Terms & Conditions and Privacy Policy. I consent that Picks And Parlays may use third-party services to process my data.

Terms & Conditions

Troy vs Clemson Pick

Despite the loss in week 1, Clemson is one of the best teams in the country and will get back to their winning ways this week. Look for Clemson to dominate this game on both sides of the ball as they come into this game with a chip on their shoulder. Take the tigers and get their first victory of the season this week as they blow Troy out, leading to the wind and cover. Final Score Prediction, Clemson Tigers win and cover 56-7.

Betting on College Football?

Bet with other College Football fans at the best sportsbooks
Sign up today and get started with the latest college football sportsbook promos

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

Min. Deposit $5

Wagering 1x Deposit

Cashable No

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit mdgamblinghelp.org (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ DC, KY, WV). Void where prohibited. Gambling problem? Call 1-800-GAMBLER or visit www.gamblersanonymous.org . Must be 21+ in NJ, PA, MI, or WV. $10 first deposit req. Bonus issued as non-withdrawable bonus spins which expire 7 days after receipt. Restrictions apply. Contact 1-877-770-7867 (LA).

Min. Deposit $5

Odds Requirements -500

Cashable No

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/KY/NH/PR/WY). Void in NH/OR/ONT/PR. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $100 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: Promos | DraftKings Sportsbook . Ends 5/31/26 at 11:59 PM ET.