Tulane at Memphis Picks and Predictions for Friday, November 7, 2025

By: David Anicetti Published 11/02/2025, 08:10 PM ET
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The Tulane Green Wave (6–2, 3–1 American Athletic Conference) visit the No. 25 Memphis Tigers (8–1, 4–1 AAC) on Friday night in a key conference matchup. Tulane is coming off a 48–26 road loss at UTSA, while Memphis has won two straight, including a 38–14 win at Rice and a 34–31 victory over South Florida. Score the winning touchdown with our college football picks.

Game Information for Tulane vs Memphis

Kickoff: 9:00 PM ET, November 7

Where: Simmons Bank Liberty Stadium, Memphis, TN

TV: ESPN

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Tulane Preview

Quarterback Jake Retzlaff averages 202.8 passing yards per game (1,622 yards, seven touchdowns, three interceptions) and adds 64.1 rushing yards per game (513 yards, nine touchdowns). Running back Javin Gordon averages 41.0 rushing yards (328 yards, three touchdowns), while Zuberi Mobley adds 163 yards and two scores. The offense is performing well behind Retzlaff’s mobility, but it has allowed pressure that limits deeper passing attempts. Omari Hayes averages 47.0 receiving yards per game (376 yards, one touchdown), and Shazz Preston adds 329 yards and a score.

On defense, safety Jack Tchienchou averages 6.4 tackles per game (51 total), and linebacker Harvey Dyson has 4.5 sacks. The Green Wave defense has been solid against the run but inconsistent defending against the pass, which will be tested against Memphis’ balanced attack.

Memphis Preview

Quarterback Brendon Lewis averages 207.7 passing yards per game (1,869 yards, 10 touchdowns, four interceptions) and 62.4 rushing yards (562 yards, eight touchdowns). Running backs Sutton Smith (515 yards, six touchdowns) and Greg Desrosiers Jr. (450 yards, seven touchdowns) form a productive rotation that has helped the Tigers have a strong running attack. Wide receiver Cortez Braham Jr. averages 70.2 receiving yards per game (632 yards, seven touchdowns), while Jamari Hawkins has 450 yards receiving.

Linebacker Sam Brumfield averages 7.3 tackles per game (66) with 4.5 sacks, and defensive back Kamari Wilson has two interceptions. Memphis’ defense has improved in red-zone situations, holding teams to field goals rather than touchdowns in its last two games.

Tulane at Memphis Prediction

Tulane’s offense has relied on Retzlaff’s dual-threat production, but Memphis has been more productive on both sides of the ball and more consistent on third down. The Tigers’ running attack and the defense’s recent red-zone success will help lead Memphis to the win. Final Score Prediction: Memphis Tigers win and cover ATS, 31–20.

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Best Picks

  • Memphis Tigers -6.5
  • Under 56.5 total point
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