Tulane at Tulsa Picks and Prediction for Saturday, September 27, 2025

By: Jake Allman Updated 09/27/2025, 01:26 AM ET
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Tulane vs Tulsa Game Information

Tulane heads to Chapman Stadium on Saturday to face Tulsa in an American Athletic clash. The Green Wave are 3-1 overall and open their conference slate against a Golden Hurricane squad sitting at 2-2. Kickoff is set for 4:00 PM ET on ESPNU with warm conditions expected. ESPN’s analytics heavily back Tulane, giving them an 89.2% chance to win. Saturday success begins with free college football picks you can rely on.

Tulane Preview

Tulane has won three of four contests. Jake Retzlaff has been the focal point of the attack, throwing for 522 yards and rushing for 288 yards with six touchdowns. His dual-threat ability provides consistent threats in the red zone. The Green Wave showed offensive strength in victories over Duke and South Alabama, scoring 30-plus points in each. Omari Hayes has been the leading target in the passing game with 143 yards, while the defense has been up and down, allowing 45 to Ole Miss but clamping down against Northwestern and Duke earlier.

Tulsa Preview

Tulsa enters off a confidence-boosting road win at Oklahoma State, where the Golden Hurricane used timely stops and a strong run game. Baylor Hayes has thrown for 542 yards with three touchdowns, but has two interceptions. Dominic Richardson has provided stability with 442 rushing yards and two touchdowns, while Zion Booker has emerged as the primary receiver with 273 yards on 29 catches. Tulsa’s defensive front has been active, with J’Dan Burnett registering five sacks and linebacker Ray Coney leading the team with 49 tackles.

Tulane vs Tulsa Prediction

Retzlaff’s rushing ability, combined with Tulane’s knack for closing drives, puts pressure on a Tulsa defense that has been inconsistent against the run. Richardson is critical for Tulsa’s chances to keep pace, but if Tulane limits early-down yardage, the Golden Hurricane may struggle to sustain drives. Tulsa showed toughness at Oklahoma State, but Tulane’s balance makes this matchup tougher to manage across four quarters. Tulane’s tempo and Retzlaff’s playmaking give the Green Wave a strong chance to cover, while both offenses can push the score above the posted total.

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Prediction: Tulane 34, Tulsa 20

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Best Picks:

  • Tulane -10.5
  • Over 51.5.
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