USC vs Purdue Picks and Predictions for Saturday, September 13, 2025

Use Code PPWC

USC vs Purdue Game Information

USC Trojans carry an undefeated record on the road this week with a game in West Lafayette against the Purdue Boilermakers in Ross-Ade Stadium at 3:30 PM. The USC Trojans are undefeated through two games coming into this week, following a blowout 39-point victory over Georgia Southern a week ago. Purdue stays home this week undefeated through two games after a 17-point victory against SIU in their last game. For more College News, see our College Football Picks.

USC Preview

Jayden Maiava leads the USC offense this season with 707 yards and six scores on 31 completions. Husan Longstreet has added 13 completions for 103 yards and one score. Waymond Jordan leads the team with 209 yards and two touchdowns on 21 carries, and King Miller has added seven carries for 135 yards and two touchdowns. Makai Lemon leads all receivers on the team with 11 catches for 248 yards and two touchdowns.

Purdue Preview 

Ryan Browne leads the Purdue offense this season with 481 yards and four touchdowns on 32 completions. Devin Mockobee boasts a team-high 185 yards and three touchdowns on 46 carries. Arhmad Branch leads the team with five catches for 132 yards and two scores. Michael Jackson the third has added seven catches for 79 yards and one touchdown.

USC vs Purdue Prediction

Both teams are playing good football coming into this week, as each is undefeated through two games. Expect a back-and-forth affair to happen early on before USC takes control. Look for the Trojans to pull away late to get the win, but Purdue will play well enough at home to cover the big number. Final Score Prediction, USC Trojans win, but the Purdue Boilermakers cover 42-31.

Betting on College Football?

• Bet with other College Football fans at the best sportsbooks
• Sign up today and get started with the latest college football sportsbook promos

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code

Claim Bonus

Signup Promo Recommended BetMGM Sport Bonus

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, New York, Ontario, or Puerto Rico.

New Users – Get $350 in Bonus Bets Guaranteed - When You Bet $5 for 7 Days!

Show Bonus Code

Claim Bonus

Signup Promo Hot Offer FanDuel Sportsbook Bonus

Min. Deposit $5

Wagering 1x Deposit

Cashable No

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelplineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit mdgamblinghelp.org (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ DC, KY, WV). Void where prohibited. Gambling problem? Call 1-800-GAMBLER or visit www.gamblersanonymous.org . Must be 21+ in NJ, PA, MI, or WV. $10 first deposit req. Bonus issued as non-withdrawable bonus spins which expire 7 days after receipt. Restrictions apply. Contact 1-877-770-7867 (LA).

New DraftKings Customers: Bet $5+ Get $100 in Bonus Bets Instantly!

Show Bonus Code

Claim Bonus

Signup Promo Hot Offer DraftKings Sport Bonus

Min. Deposit $5

Odds Requirements -500

Cashable No

GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA). Call 877-8-HOPENY/text HOPENY (467369) (NY). Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/KY/NH/PR/WY). Void in NH/OR/ONT/PR. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $100 issued as non-withdrawable Bonus Bets that expire in 7 days (168 hours). Stake removed from payout. Terms: Promos | DraftKings Sportsbook . Ends 5/31/26 at 11:59 PM ET.

Texas Rangers vs Boston Red Sox Picks and Prediction for Sunday June 14 2026

The Texas Rangers and Boston Red Sox wrap up their series on Sunday, June 14, 2026, at Fenway Park in Boston, Massachusetts. First pitch is...

Tampa Bay Rays vs Los Angeles Angels Picks and Prediction for Sunday June 14 2026

The Tampa Bay Rays and Los Angeles Angels continue their series on Sunday, June 14, 2026, at Angel Stadium in Anaheim, California. First pitch is...

Chicago Cubs vs San Francisco Giants Picks and Prediction for Sunday June 14 2026

The Chicago Cubs and San Francisco Giants meet on Sunday, June 14, 2026, at Oracle Park in San Francisco, California. First pitch is scheduled for...

Colorado Rockies vs Athletics Picks and Prediction for Sunday June 14 2026

The Colorado Rockies and Athletics continue their series on Sunday, June 14, 2026, at Las Vegas Ballpark in Las Vegas, Nevada. First pitch is scheduled...

St. Louis Cardinals vs Minnesota Twins Picks and Prediction for Sunday June 14 2026

The St. Louis Cardinals and Minnesota Twins continue their series on Sunday, June 14, 2026, at Target Field in Minneapolis, Minnesota. First pitch is scheduled...

Philadelphia Phillies vs Milwaukee Brewers Picks and Prediction for Sunday June 14 2026

The Philadelphia Phillies and Milwaukee Brewers meet on Sunday, June 14, 2026, at American Family Field in Milwaukee, Wisconsin. First pitch is scheduled for 2:10...

NBA Finals Game 5 Picks & Predictions Knicks vs Spurs | Steve Seagrave

MLB Picks Today Guardians-Tigers, Rays-Angels & Phillies-Brewers | David Delano

Best Picks:

• Purdue Boilermakers +21.5
• Over 59.5