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USC vs UCLA Picks and Predictions for Saturday, November 29, 2025

By: Cameron Ross Published 11/25/2025, 11:56 PM ET

UCLA vs USC Information

The UCLA Bruins will end the season this week, playing a road game against the USC Trojans in Los Angeles. UCLA has just three wins through 11 games played, riding a 4-game skid into this week following your 34-point loss to Washington and their last outing. USC returns home this week with eight wins and three losses, ranked #15 in the nation, following a 15-point road loss to Oregon last week to end a three-game winning streak. Stay in the news with our College Football Picks.

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UCLA Preview

Nico Iaamaleava leads the UCLA offense this season with 1728 yards and 12 scores on 181 completions to go along with the team high 490 yards and four touchdowns on 101 carries. Jalen Berger is the best running back on the team this season and has added 307 yards and two touchdowns on 74 carries. Kwazi Gilmer leads the team with 462 yards and three touchdowns on 40 receptions this season. Betting on sports and on UCLA is easy, but even easier if you use the best sportsbooks.

USC Preview

Jayden Maiava leads the USC offense this season with 3174 yards and 21 scores on 226 completions. King Miller is the top ball carrier on the team with 749 yards and five touchdowns on 114 carries. Waymond Jordan has added 88 carries for 576 yards and five touchdowns. Makai Lemon leads the team with 1124 yards and 10 scores from 78 receptions. Make sure you know about how the fans are looking on prediction markets for USC with the Novig promo code.

UCLA vs USC Prediction

USC is the better team in this matchup and will get the win at home this week. Look for the Trojans to control this game on both sides of the ball against a terrible UCLA team. USC will want to fine-tune itself heading into bowl season and will roll past UCLA this week. Take USC to finish the regular season Saturday with a win and cover at home against an in-state opponent. Final Score Prediction, USC Trojans win and cover 48-13. Make sure when you place your bet on UCLA vs USC you are using the BetMGM bonus code.

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Best Picks:

  • USC Trojans -21.5
  • Over 59.5
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