UTSA at South Florida Picks and Predictions for Thursday, November 6, 2025
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The UTSA Roadrunners (4–4, 2–2 American) visit the South Florida Bulls (6–2, 3–1 American) on Thursday night in a conference matchup. UTSA is coming off a 48–26 win over Tulane after a bye week and a previous stretch that included a 61–13 win over Rice and losses at North Texas and Temple. South Florida most recently fell at Memphis (34–31) after four straight wins. Get all the best college football picks.
Game Information for UTSA vs South Florida
Kickoff: 7:30 PM ET, November 6
Where: Raymond James Stadium, Tampa, FL
TV: ESPN
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UTSA Preview
Quarterback Owen McCown averages 210.0 passing yards per game (1,680 yards) with 17 touchdowns and four interceptions while completing 67.5% of his passes. Running back Robert Henry Jr. averages 119.4 rushing yards per game (955 yards) at 8.0 yards per carry with nine touchdowns, giving the Roadrunners a solid running attack. Devin McCuin averages 57.5 receiving yards per game (43 receptions, 460 yards, six touchdowns), and AJ Wilson stretches the field (20.9 yards per catch, three touchdowns).
Linebacker Shad Banks Jr. leads the defense and averages 6.4 tackles per game (51) with two interceptions. Linebacker Nnanna Anyanwu has five sacks, part of a front that has improved on passing downs in recent games. UTSA still allows big plays at times, so third stops are a priority against a quarterback who runs.
South Florida Preview
Quarterback Byrum Brown averages 245.5 passing yards per game (1,964 yards, 17 touchdowns, six interceptions) and adds 74.5 rushing yards per game (596 yards, eight touchdowns). The Bulls spread the ball: Chas Nimrod averages 58.3 receiving yards per game (466 yards, three touchdowns), Keshaun Singleton averages 56.4 (451 yards, three touchdowns), and Jeremiah Koger has been a red-zone target (337 yards, five touchdowns). South Florida is averaging over 40 points per game behind Brown’s dual-threat production and big-play receivers.
Linebacker Mac Harris anchors the defense and averages 8.6 tackles per game (69) with 5.5 sacks. Safety Jarvis Lee has two interceptions, while the front seven has been a menace to opposing QBs (13 team sacks). The Bulls have tightened up in the second half during wins, holding opponents to limited scoring after the break.
UTSA at South Florida Prediction
UTSA brings a productive rushing attack with Henry and an accurate passer in McCown, but South Florida’s spread run-pass game with Brown is harder to contain for four quarters. The Bulls’ receivers and Brown’s rushing will make the difference at home. Final Score Prediction: South Florida Bulls win and cover ATS, 38–24.
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Best Picks
- South Florida Bulls -6.5
- Over 58.5 total points
- Byrum Brown anytime touchdown
