Villanova vs Penn State Picks and Predictions for Saturday, September 13, 2025
Villanova vs Penn State Game Information
The Villanova Wildcats will be on the road for the first time this week as they take on the number 2-ranked Penn State Nittany Lions in Beaver Stadium at 3:30 PM. Villanova is undefeated this season, coming into this week following a narrow 7-point victory at home against Colgate to start the year. Penn State is ranked number 2 in the nation, undefeated through two games, following a 34-point blowout victory against FIU this past week at home. Stay in the news with our College Football Picks.
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Villanova Preview
Pat McQuaide leads the Villanova offense this season with 299 yards and one touchdown on 18 completions. David Avit has led the way on the ground for the Wildcats with 15 carries for 49 yards this season. Luke Colella has posted a team-leading 124 yards on five catches, while Lucas Kopecky has accounted for five catches for 98 yards and one touchdown.
Penn State Preview
Drew Allar leads Penn State this season with 417 yards and three touchdowns on 41 completions. Kaytron Allen is the top ball carrier on the roster with 187 yards and two scores on 24 carries. Nicholas Singleton has chipped in heavily with 28 carries for 95 yards and three scores. Kyron Hudson leads the team with 11 catches for 126 yards and one touchdown.
Villanova vs Penn State Prediction
Penn State is the second-best team in the country and will continue its dominance this week against Villanova. Look for the Nittany Lions to control this game from the opening minutes as they roll to the easy win. Villanova will be unable to keep up as Penn State runs the score up, leading to their third victory of the season following the win and cover at home. Final Score Prediction, Penn State Nittany Lions win and cover 63-3.
| # | Handicapper | Profit |
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| 1 |  Rob Vincilleti | +2,576.00 |
| 2 |  Ross Benjamin | +1,654.00 |
| 3 |  Earle Sports Bets | +1,541.00 |
| 4 |  Dan Kaiser | +1,397.00 |
| 5 |  Mark Ruelle | +784.00 |
Best Picks:
- Penn State Nittany Lions ATS
- Over
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