Wake Forest vs Purdue Picks and Predictions for Saturday, September 12th, 2026

By: Cameron Ross Published 09/11/2026, 12:22 AM ET

Wake Forest vs Purdue Game Information

The Wake Forest Demon Deacons will be on the road this Saturday, facing the Purdue Boilermakers at Ross-Ade Stadium in West Lafayette, IN, at 12:00 PM. Wake Forest comes into Game 2 of the year undefeated following a 38-16 victory against Akron. Purdue will remain at home this week after opening the season with a 44-19 victory against Indiana State.  For other College Football News, see our College Football Picks.

Wake Forest Preview

Defensively, Wake Forest gave up 16 points on 305 total yards while forcing 1 turnover last week. Offensively, the Demon Deacons were outstanding, scoring 38 points on 559 total yards. Gio Lopez led the way, completing 21 of 32 passes for 350 yards and 3 touchdowns and ran the ball 7 times for 39 yards. Ty Clark III was the top ball carrier with 105 yards on 7 carries. Deuce Lawrence chipped in heavily with 52 yards and 1 touchdown on 13 carries. Carlos Hernandez led the team with 165 yards and 1 touchdown on 5 receptions.  Antonio Meeks added 93 yards and 1 score on 3 grabs, while Kam Shanks chipped in 5 catches for 55 yards and 1 touchdown.

Purdue Preview

Defensively, Purdue gave up 19 points on 284 total yards and forced 1 turnover last week. Offensively, the Boilermakers scored 44 points on 523 total yards. Ryan Browne led the Purdue offense, completing 23 of 29 passes for 317 yards and 3 touchdowns. Evan Chuba completed 4 passes for 29 yards. Fame Ijeboi led the rushing attack with 87 yards and 1 touchdown on 11 carries. Asaad Waseem led the team with 107 yards and 1 touchdown on 6 receptions. Tra'Mar Harris added 22 yards and 1 touchdown on 2 catches, and Chauncey Magwood pulled in 1 pass for 6 yards and a score.

Wake Forest vs Purdue Pick

Purdue will thrive in front of their home fans Saturday afternoon against a good Wake Forest team. Look for the Boilermakers to set the tone early and control this game from the outset. Take Purdue Saturday at home to do the work to stay undefeated as they get the win and cover.

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  • Pick: Purdue Boilermakers +3
  • Secondary: Under 49.5

Final Score Prediction: Purdue Boilermakers win and cover 24-21.

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