Weber State vs Arizona Picks and Predictions for Saturday September 6 2025
Weber State at Arizona Preview
The Weber State Wildcats take on the Arizona Wildcats in a Week 2 college football matchup on September 6, 2025, at Arizona Stadium in Tucson, Arizona. Kickoff is set for 7:00 p.m. MST, airing on ESPN+. Arizona is a heavy 31.5-point favorite with a moneyline of -5000, and the over/under is set at 54.5 points, per BetMGM Sportsbook. This non-conference clash features an FCS Weber State team coming off a lopsided loss against an Arizona squad aiming to build momentum after a Week 1 win. Elevate your betting game with expert College Football Betting Picks for top insights and winning strategies.
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Weber State Analysis
Weber State opened the 2025 season at 0-1, falling 45-10 to James Madison in Week 1. The Wildcats struggled offensively, managing just 148 total yards, and were outmatched defensively, allowing 458 yards. In 2024, Weber State finished 4-8 overall with a 3-5 Big Sky Conference record, indicating challenges in sustaining consistency against stronger opponents.
The Wildcats’ offense averaged 20.3 points and 310.2 yards per game in 2024, with quarterback Jackson Gilkey, a transfer, throwing for 112 yards and a touchdown in Week 1. Running back Zach Hrbacek provides a ground presence, but the unit struggled against James Madison’s defense. Defensively, Weber State allowed 27.1 points per game last season and was gashed for 313 rushing yards in their opener, a major concern against Arizona’s potent run game.
Arizona Analysis
Arizona started 2025 at 1-0, defeating Hawaii 24-13 in Week 1. The Wildcats showcased a strong rushing attack and a solid defense, holding the Rainbow Warriors to 256 total yards. In 2024, Arizona went 4-8 overall, but their Week 1 performance under second-year coach Brent Brennan suggests improvement, particularly at home where they were 3-3 last season.
Arizona’s offense averaged 24.8 points and 391.5 yards per game in 2024, led by quarterback Noah Fifita, who threw for 199 yards and three touchdowns against Hawaii. Running back Quali Conley added 112 yards, and the offensive line protected well, allowing no sacks. Defensively, Arizona allowed 25.6 points per game last season but showed promise in Week 1, holding Hawaii to 3.9 yards per rush.
Standout Players and Key Injuries
For Weber State, quarterback Jackson Gilkey is the offensive leader, though his Week 1 output was limited, and running back Zach Hrbacek offers potential with 65 yards per game in 2024. Offensive lineman Gavin Ortega, an all-conference talent, anchors the line. For Arizona, quarterback Noah Fifita drives the offense with 2,869 yards and 25 touchdowns in 2024, while wide receiver Tetairoa McMillan, a projected NFL first-rounder, had 88 catches last season. Linebacker Jacob Manu led with 87 tackles.
Weber State reports no major injuries, but their youth and inexperience were evident in Week 1. Arizona’s running back Kedrick Reescano is questionable with a foot injury, potentially limiting their backfield depth.
| # | Handicapper | Profit |
|---|---|---|
| 1 |  Rob Vincilleti | +2,063.00 |
| 2 |  Chip Chirimbes | +1,495.00 |
| 3 |  Ross Benjamin | +1,490.00 |
| 4 |  Earle Sports Bets | +1,379.00 |
| 5 |  Dan Kaiser | +1,323.00 |
Prediction Reasoning
Arizona’s talent and home-field advantage make them overwhelming favorites. Their Week 1 performance, particularly the rushing attack led by Conley, should exploit Weber State’s run defense, which allowed over 300 yards against James Madison. Fifita’s precision passing and McMillan’s big-play ability will further stretch the Wildcats’ secondary. Weber State’s offense, still gelling under Gilkey, is unlikely to keep pace, especially after managing just 10 points against an FBS foe. Arizona’s motivation to avoid a repeat of last year’s close call against FCS Northern Arizona (38-26) fuels a dominant effort. Final Score Prediction: Arizona 45, Weber State 13.
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