Western Kentucky vs Indiana Picks and Prediction for Saturday, September 19, 2026
The Western Kentucky Hilltoppers visit the 4th-ranked Indiana Hoosiers on Saturday at Memorial Stadium in Bloomington, with the opening kickoff scheduled for 4:00 PM ET on Peacock. Western Kentucky is 0-2 overall and 0-0 in Conference USA after a 70-20 road loss to Georgia, following a 49-14 loss at Nevada. Indiana is 2-0 overall and 0-0 in the Big Ten after shutting out Howard 55-0, one week after beating North Texas 52-16. Get ready for Saturday’s matchup with our free NCAAF picks.
Western Kentucky Hilltoppers
Western Kentucky has scored 34 points through two games while averaging 159 passing yards and 137 rushing yards per game. Rodney Tisdale Jr. has completed 30 of 54 passes for 234 yards with one interception, while Brock Glenn has thrown for 84 yards, one touchdown and one interception. Ajay Allen leads the ground game with 121 yards and two touchdowns on 32 carries. Cameron Flowers has a team-high 74 receiving yards, while Jonathan Stafford Jr. has caught eight passes for 65 yards.
The Hilltoppers have allowed 59.5 points per game after surrendering 49 to Nevada and 70 to Georgia. Western Kentucky has yet to record a sack and has produced one interception. Justin Brown has that interception and 11 tackles, while Jaylen Lewis leads the defense with 13 tackles and has forced a fumble. Jaylen Wester has six tackles and two forced fumbles. The Hilltoppers now face an Indiana offense that has scored 107 points through two games.
Injuries: WR K. Hutchinson (undisclosed) is questionable.
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Indiana Hoosiers
Indiana has averaged 53.5 points through two games while producing 220 passing yards and 217.5 rushing yards per game. Josh Hoover has completed 19 of 27 passes for 376 yards, eight touchdowns and no interceptions. Charlie Becker has caught seven passes for 145 yards and five touchdowns, while Nick Marsh has 88 yards and two scores. Turbo Richard leads the rushing attack with 166 yards and three touchdowns on 26 carries, while Lee Beebe Jr. has added 150 yards on 30 attempts.
The Hoosiers have allowed eight points per game after beating North Texas 52-16 and shutting out Howard. Indiana has recorded six sacks and two interceptions. Keishaun Calhoun leads the pass rush with two sacks, while Jacob Savage, Tobi Osunsanmi, Tyrique Tucker and Mario Landino each have one. Rolijah Hardy and Quan Sanks have interceptions, with Hardy returning his 19 yards for a touchdown. Isaiah Jones leads Indiana with 17 tackles, while Hardy has added 12.
Injuries: K Nico Radicic (back) and WR Nick Marsh (undisclosed) are questionable.
Western Kentucky vs Indiana Prediction
Indiana has major statistical advantages on both sides of the ball. The Hoosiers are averaging 53.5 points and have allowed only 16 total points, while Western Kentucky has been outscored 119-34. Hoover has eight touchdown passes without an interception, and Indiana also has two running backs with at least 150 rushing yards. Western Kentucky has struggled to slow either opponent and now faces another high-scoring offense. Indiana can attack through Hoover or the ground game, while the Hoosiers' six sacks create another difficult matchup for the Hilltoppers. Indiana will take control early and win comfortably at home. Final Score Prediction: Indiana Hoosiers win, 57-7.
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