William & Mary vs Duke Picks and Predictions for Saturday, September 26th, 2026

William & Mary vs Duke Game Information

The William and Mary Tribe will be on the road Saturday afternoon, playing the Duke Blue Devils at Wallace Wade Stadium in Durham, NC, at 3:30 PM. William and Mary enters this matchup at .500 through 4 games, riding a two-game skid after a 25-point home loss a week ago. The Duke Blue Devils stay home Saturday undefeated through their first 3 games of the season after a 28-point victory against Stanford last week. Stay in the action with our College Football Picks.

William & Mary Preview

Winston Watkins leads the William & Mary offense this season with 799 yards and 4 touchdowns on 62 completions, along with 117 yards and 2 scores on 58 carries. Carter Carroll has completed 8 passes for 37 yards. Andrew King leads the Tribe with 318 yards and 3 touchdowns on 52 carries, while Jah’Kei Chavis has added 66 yards and 2 scores on 23 carries. Kai Austin leads the receiving corps with 246 yards and 2 touchdowns on 21 catches. Khylil Johnson has added 219 yards on 11 receptions, while Luke VanAntwerp has 135 yards on 10 catches.

Duke Preview

Walker Eget leads Duke this season with 539 yards and 4 touchdowns on 42 completions. Eget has thrown only 1 interception through 71 attempts. Nate Sheppard has powered the Duke offense with 528 yards and 5 touchdowns on 82 carries, along with 62 yards and 3 scores on 9 receptions. CJ Campbell Jr. has added 98 yards on 27 carries. Jeremiah Hasley leads the Blue Devils with 177 yards on 10 catches, while Jonah Burton has contributed 124 yards and 1 touchdown on 8 receptions.

William & Mary vs Duke Pick

William & Mary has enough offensive balance to challenge Duke early, particularly with Watkins contributing as both a passer and runner. However, the Tribe must find a way to slow down Sheppard after he produced 528 rushing yards and 8 total touchdowns through Duke’s first 3 games. The Blue Devils should control the line of scrimmage and use their rushing attack to wear down William & Mary’s defense. Duke’s defensive pressure should also force Watkins into difficult third-down situations. Take the Blue Devils to pull away during the second half and record the home victory.

• Pick: Duke Blue Devils -43.5
• Secondary: Over 62.5

Final Score Prediction: Duke Blue Devils win 56-7

Betting on College Football?

• Bet with other College Football fans at the best sportsbooks
• Sign up today and get started with the latest college football sportsbook promos

Up To $1500 in Bonus Bets Paid Back if your First Bet Does Not Win

Show Bonus Code

Claim Bonus

Signup Promo Recommended BetMGM Sport Bonus

Min. Deposit $5

Cashable No

Gambling problem? Call 1-800-GAMBLER or 1-800-MY-RESET (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR). 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only (if applicable). Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. Promotional offers not available in Mississippi, Massachusetts, New York, Ontario, or Puerto Rico.

New Users – Get $250 in Bonus Bets when you wager $5 for 5 days

Show Bonus Code

Claim Bonus

Signup Promo Hot Offer FanDuel Sportsbook Bonus

Requirement New Users – Get $350 in Bonus Bets when you wager $5 for 7 days ($50 Bonus Bets per day)

Cashable No

Gambling Problem? Call 1-800-GAMBLER or 1-800-MY-RESET. Call 1-888-789-7777 or visit ccpg.org/chat (CT). Hope is here. GamblingHelpLineMA.org or call (800) 327-5050 for 24/7 support (MA). Visit www.mdgamblinghelp.org (MD). Call 1-877-8HOPE-NY or text HOPENY (467369) (NY). 21+ (18+ D.C., KY, WY) and present in select states (for KS, in affiliation with Kansas Star Casino). First online real money wager only. Min $5 wager required for 5 consecutive days.$5 first deposit required. Bonus issued as nonwithdrawable bonus bets which expire 7 days after receipt. Restrictions apply. See terms at sportsbook.fanduel.com. Call 1-877-770-7867 (LA). ™/© 2026 MLB

New DraftKings Customer: SPEND $5, GET $200 IN BONUSES

Show Bonus Code

Claim Bonus

Signup Promo Hot Offer DraftKings Sport Bonus

Min. Deposit $5

Requirement New DraftKings Customer Offer: SPEND $5, GET $200 IN BONUSES ($50 in Bonus Bets every 7 days for 21 days)*

Cashable No

To be eligible for DraftKings Sportsbook and the Promotion, you must be physically located in AR, AZ, CO, CT, DC, IA, IL, IN, KS, KY, LA (select parishes), MA, MD, ME, MI, MO, NC, NJ, NH, NY, OH, OR, PA, PR (residents only), TN, VA, VT, WY, WV, CA-ONT or CA-AB (each an “Eligible Jurisdiction” or, collectively, the “Eligible Jurisdictions”). Must be 21+ years of age or older (18+ if in DC/NH/PR/WY/CA-AB) (19+ in CA-ONT). GAMBLING PROBLEM? CALL 1-800-GAMBLER or 1-800-MY-RESET, (800) 327-5050 or visit gamblinghelplinema.org (MA) Please Gamble Responsibly. 888-789-7777/visit ccpg.org (CT), or visit www.mdgamblinghelp.org (MD), 1-800-981-0023 (PR). 21+ and present in most states. (18+ DC/NH/PR/WY). Void in CAN. Eligibility restrictions apply. On behalf of Boot Hill Casino (KS). Pass-thru of per wager tax may apply in IL. 1 per new DraftKings customer. $5+ first-time bet req. Max. $200 issued as non-withdrawable Bonus Bets. Stake removed from payout. Reward issued as $50 in Bonus Bets every 7 days via click-to-claim for 21 days. Bonus Bets and click-to-claims expire 7 days (168hrs) after issuance. Terms: Promos | DraftKings Sportsbook . Ends 9/20/26 at 11:59 PM ET. Sponsored by DK.

Boise State vs Western Michigan Picks and Predictions for Saturday, September 26th, 2026

Boise State vs Western Michigan Game Information The Boise State Broncos will travel to Kalamazoo on Saturday for a 3:30 PM matchup inside Waldo Stadium...

Los Angeles Rams vs Denver Broncos Picks, Prediction, Odds, and Line Movement for Sunday September 27 2026

The Los Angeles Rams head to Mile High to face the Denver Broncos in a matchup that looks like a potential photo finish, and this...

Las Vegas Raiders vs New Orleans Saints Picks, Prediction, Odds, and Line Movement for Sunday September 27 2026

The Las Vegas Raiders and New Orleans Saints meet in a matchup between two of the hottest teams against the spread, and this Raiders vs...

Baltimore Ravens vs Dallas Cowboys Picks, Prediction, Odds, and Line Movement for Sunday September 27 2026

The Baltimore Ravens and Dallas Cowboys meet at Maracana Stadium in Rio de Janeiro, Brazil, in what figures on paper to be one of the...

Minnesota Vikings vs Tampa Bay Buccaneers Picks, Prediction, Odds, and Line Movement for Sunday September 27 2026

The Minnesota Vikings travel to Tampa to face the Buccaneers in a matchup between one of the hottest teams in football and one of the...

Arizona Cardinals vs San Francisco 49ers Picks, Prediction, Odds, and Line Movement for Sunday September 27 2026

The Arizona Cardinals travel to Levi's Stadium in Santa Clara to face the San Francisco 49ers in an NFC West matchup where the two teams...

Today's MLB BEST Bets: Brewers vs Padres + Royals vs Dodgers Picks and Predictions

Daily Profit: Can The Seahawks REPEAT?? NFC West Betting Preview