William & Mary vs Virginia Picks and Predictions for Saturday, September 13, 2025
The William & Mary Tribe visits Scott Stadium in Charlottesville, Virginia, on Saturday to play the Virginia Cavaliers at 12:00 PM ET on ACC Network. William & Mary is 1-1 off a one-point win (28-27) over Maine after a competitive road loss (23-21) at Furman, while Virginia is 1-1 with a commanding opening win (48-7) over Coastal Carolina and a tough defeat (35-31) at NC State. Keep up to date with all the College Football action, with our College Football predictions.
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William & Mary Preview
William & Mary has a dual-threat quarterback. Tyler Hughes has thrown for 337 yards with three touchdowns and added 130 yards on the ground with one rushing score. Rashad Raymond is second in rushing with 124 yards and two touchdowns. Deven Thompson has a team-best 86 yards receiving and one touchdown reception.
The William & Mary defense is led by linebacker Luke Banbury with 30 tackles and linebacker Harrison Johnson with 24. William and Mary have made for quarterback sacks with four different players posting one quarterback sack apiece. The Tribe have made one interception. William & Mary will have a tough time containing the Virginia offense and must step up against the passing game.
Virginia Preview
Virginia’s offense has started fast behind QB Chandler Morris, who has 521 passing yards with three touchdowns and one interception. The receiving corps is led by Cam Ross with 164 yards and one touchdown reception, while Trell Harris has 145 yards receiving. The ground game is led by J’Mari Taylor with 182 yards and five rushing TDs, including a 66-yard burst. That balance makes the Cavaliers difficult to defend against.
Defensively, linebacker Landon Danley leads in tackles with 13 and linebacker James Jackson has 11. Virginia has just one quarterback sack with end Fisher Camac and linebacker Maddox Marcellus each with 0.5. Safety Ethan Minter has Virginia's only interception.
William & Mary vs Virginia Prediction
William & Mary can move the ball with Hughes’ legs, but Virginia’s speed on the edge and its wide receiver corps, who can stretch the field, will be too much for the Tribe to keep pace. Look for a double-digit victory at home by the Cavaliers. Final Score Prediction: Virginia Cavaliers win and cover ATS 44-7.
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