Wyoming vs Colorado State Picks and Predictions for Saturday, September 5th, 2026

By: Cameron Ross Published 09/04/2026, 11:58 PM ET

Wyoming vs Colorado State Game Information

The Wyoming Cowboys will be on the road Saturday night for a 6:00 PM matchup inside Canvas Stadium in Fort Collins, CO, against the Colorado State Rams. Wyoming comes into this year looking to improve after a lackluster season last year. After starting 2025 2-0, Wyoming finished 4-8 after losing 5 of its last 6 regular-season games. The Colorado State Rams open the 2026 season Saturday night looking to improve on last year's struggles. Colorado State won just 2 games last year and lost 6 games in a row to end the season following a 21-point loss to Air Force in late November. Stay in the news with our College Football Picks.

Wyoming Preview

Last year’s quarterback, Kaden Anderson, entered the portal after last year and is no longer on the roster. Transfer Tyler Hughes is the new quarterback for Wyoming this year after 2330 yards and 20 scores on 240 completions at William & Mary a year ago. Sophomore Samuel Harris returns this season for Wyoming after leading the team last year with 558 yards and 1 score on 100 carries. Jackson Holman is the top returning receiver for Wyoming this year after 139 yards on 13 catches last season.

Colorado State Preview

Transfer Hauss Hejny will take over the Colorado State offense this year, playing for his third team in 3 years. Hejny had limited action a year ago, completing just 5 passes for 96 yards and 1 score with Oklahoma State. Darius Curry returns this year for Colorado State after compiling 25 yards on 17 carries a year ago. Tommy Maher is the top receiver back this season after 358 yards on 32 catches last year.

Wyoming vs Colorado State Pick

Colorado State will have the home-field advantage in what should be a physical and competitive rivalry matchup. Wyoming will attempt to slow the game down, but the Rams should generate enough offense to create separation during the second half. Look for Colorado State’s defense to make the decisive stops late as the Rams protect their home field, leading to the win and cover Saturday night.

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  • Pick: Colorado State Rams -3
  • Secondary:  Under 46.5

Final Score Prediction:  Colorado State Rams win and cover, 27-13.

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