Arizona Cardinals vs Seattle Seahawks Picks and Prediction for Sunday November 8, 2026
The Arizona Cardinals will be on the road Sunday afternoon for an NFC West matchup against the Seattle Seahawks inside Lumen Field in Seattle, Washington. The game is scheduled to kick off at 4:25 PM ET. Arizona enters Sunday at 3-5 overall following a three-point overtime victory against Dallas last week. Seattle remains home at 4-4, having lost three of its last four games following a 17-point loss to Chicago last time out. The Seahawks are 8.5-point home favorites at -470 on the money line, while Arizona is listed at +360. The total is set at 39.5 points. Stay up to date with our NFL Picks.
Arizona Cardinals Preview
With Jacoby Brissett no longer on the Arizona roster, Gardner Minshew II leads the team with 188 passing yards and three touchdowns on 17 completions this season. Tyler Allgeier is the top ball carrier with 323 yards and two touchdowns on 72 carries. Jeremyah Love is second on the team with 268 yards and one score on 76 carries. Trey McBride leads the Arizona receiving corps with 544 yards and five touchdowns on 66 receptions. Michael Wilson has added 486 yards and two scores on 45 catches.
Offensively, Arizona erupted last week, compiling 467 total yards and scoring 33 points, including 20 in the fourth quarter. Defensively, the Cardinals did enough, allowing 30 points on 261 total yards. Jacoby Brissett completed 10 passes for 119 yards before Gardner Minshew II took over, completing 17 passes for 188 yards and three touchdowns to lead Arizona to the victory. Tyler Allgeier led the ground game with 147 yards and one touchdown on 11 carries, along with 44 yards and another score on five receptions. Michael Wilson led the receiving corps with 111 yards and one touchdown on eight catches, while Trey McBride added 72 yards and one score on seven receptions.
Seattle Seahawks Preview
Sam Darnold leads the Seattle offense this season with 1,478 passing yards and 10 touchdowns on 127 completions. Drew Lock has appeared in two games for Seattle, compiling 422 yards and four touchdowns on 35 completions. Emmanuel Wilson is the top ball carrier on the roster with 403 yards and three touchdowns on 111 carries. Jaxon Smith-Njigba leads the Seattle receiving corps with 985 yards and nine touchdowns on 64 receptions. Cooper Kupp has added 206 yards and two scores on 19 catches.
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Offensively, Seattle struggled a week ago, scoring just 17 points on 252 total yards after committing one turnover and converting only one third down. Defensively, the Seahawks were outmatched, allowing 34 points, including 21 in the second half, on 363 total yards. Sam Darnold led the Seattle offense with 188 passing yards and two touchdowns on 17 completions. Jaxon Smith-Njigba led the receiving corps with 118 yards and one touchdown on six catches.
Arizona Cardinals vs Seattle Seahawks Pick
Seattle desperately needs a win to end its recent struggles and should find a way to get the job done despite Sam Darnold remaining out. However, Arizona has shown improvement offensively and should be able to ride the Minshew magic again this week against the defending Super Bowl champions. Look for the Cardinals to keep this game competitive, as an outright upset is not out of the question. Seattle has enough talent and depth to secure the home victory, but Arizona should do enough offensively to stay within the number. Take the Cardinals to cover the spread on the road Sunday.
- Pick: Arizona Cardinals +8.5
- Secondary: Under 39.5
Final Score Prediction: Seattle Seahawks win, but the Arizona Cardinals cover 20-14.
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