Carolina Panthers vs New England Patriots Picks and Prediction for Sunday September 28 2025

By: Thomas Pemberton Updated 09/26/2025, 01:06 PM ET
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The Carolina Panthers head to Foxborough this Sunday to take on the New England Patriots. The Patriots are -6 home favorites and the total is set at 44 points. The Panthers are hoping to find momentum as they are coming off their first win of the season. While the Patriots are seeking their first home win of the season. Don’t miss your chance to elevate your NFL experience with free NFL picks that ignite your desire to win.

Carolina Panthers Preview

The Carolina Panthers are 1-2 on the season with a 0-2 road record. Carolina won their first game of the season last week when they shut out the Atlanta Falcons 30-0. QB Bryce Young threw for 121 yards in the win and rushed for a touchdown. Young has 4 passing touchdowns on the season with 3 interceptions. WR Tetairoa McMillian leads Carolina with 14 catches and 216 receiving yards. While Hunter Renfrow has two touchdown catches. The Panthers had given up at least 26 points in two straight games prior to shutting out the Falcons. Carolina is 2-1 against the spread on the season.

New England Patriots Preview

The New England Patriots are 1-2 on the season with a 0-2 home field record. The Patriots lost to the Steelers 21-14 at home last week. QB Drake Maye threw for 268 yards in the loss with 2 touchdowns and an interception. Maye has 5 touchdowns with 2 interceptions on the season. The Patriots have been outscored 41-27 on their home field. Stefon Diggs and Hunter Henry both lead New England on the season with 13 catches each.

Panthers vs Patriots Free Picks & Prediction

The Carolina Panthers are hoping for a similar performance that they had in their win last week. The Panthers scored in every quarter while their defense locked down the Falcons. New England is struggling to find a way to win on their home field and may be in trouble with another motivated team coming to town. Take those free points in what should be a tight game.

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Final Score Prediction: New England Patriots win 21-20 but the Carolina Panthers cover ATS

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Panthers vs Patriots Best Free Picks

  • Carolina Panthers +6
  • UNDER 44
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