Dallas Cowboys vs Detroit Lions Picks and Prediction for Thursday December 4 2025

By: Eddie Kline Published 12/03/2025, 01:23 AM ET

Cowboys Preview

The week 14 NFL schedule will get started on Thursday night with a matchup between the Dallas Cowboys and the Detroit Lions from Ford Field. Get ready for all the football action with our NFL Picks. The Cowboys (6-5-1) are riding a three-game winning streak and trail Philadelphia by 1.5 games for first place in the NFC East Division. On Thanksgiving Day, Dallas rolled up 454 yards of total offense during a 31-28 home victory versus Kansas City.

Dallas QB Dak Prescott overcame an early interception to throw for 320 yards and two touchdowns. WR CeeDee Lamb contributed seven receptions for a game-high 112 yards and a score. Veteran DE Jadeveon Clowney added a pair of sacks for the Cowboys.

Lions Preview

The Detroit Lions have won four of their first six home games and are two games back in the race for the top spot in the NFC North Division. The Lions (7-5) rank third in the league in total offense and are scoring a shade below 30 points per contest. On Thanksgiving Day, Detroit’s banged up offensive line allowed three sacks during a 31-24 home loss versus Green Bay.

Detroit QB Jared Goff completed 20 of 26 passes for 256 yards and two touchdowns. Jameson Williams exploded for seven catches for a game-high 144 yards and a 22-yard touchdown. RB Jahmyr Gibbs was limited to 68 rushing yards on 20 carries for the Lions.

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Cowboys vs Lions Pick

Detroit WR Amon-Ra St. Brown was forced to exit Thursday’s loss with an ankle injury and his status for this game is uncertain. These are two of the most explosive offenses in the NFL and the Cowboys rank 28th in the league in total defense. Look for the Lions to bounce back with a home victory that goes over the total. Final Score Prediction, Detroit Lions win 31-28. Betting on sports and on the Lions is easy, but even easier if you use the best sportsbooks. Make sure you know about how the fans are looking on prediction markets for the Cowboys with the social sportsbooks. Getting the most out of your bets on Lions vs Cowboys can be done by using the Fanatics Sportsbook promo code.

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