Dallas Cowboys vs Indianapolis Colts Picks and Prediction for Sunday November 8, 2026

By: Cameron Ross Published 11/07/2026, 12:06 PM ET

The Dallas Cowboys will be on the road Sunday afternoon for a matchup against the Indianapolis Colts inside Lucas Oil Stadium in Indianapolis, Indiana. The game is scheduled to kick off at 1 PM ET. Dallas enters Sunday at 3-5 overall, having lost three of its last four games following a three-point overtime loss to Arizona last time out. Indianapolis returns home at 2-6, riding a four-game losing streak following a 35-point road loss to Jacksonville. The Cowboys are 4.5-point road favorites at -225 on the money line, while Indianapolis is listed at +185. The total is set at 51.5 points. Stay in the action with our NFL Picks.

Dallas Cowboys Preview

Dak Prescott leads the Dallas offense this season with 2,046 passing yards and 14 touchdowns on 197 completions, along with 101 rushing yards and one score on 23 carries. Javonte Williams is the top ball carrier on the roster with 528 yards and eight touchdowns on 134 carries. CeeDee Lamb leads the Dallas receiving corps with 709 yards and six touchdowns on 60 catches. George Pickens has added 533 yards and two scores on 39 receptions, while Ryan Flournoy has chipped in 342 yards and two touchdowns on 30 catches.

The Dallas offense was solid last week, scoring 30 points on 261 total yards but failed to score in overtime, resulting in the loss. Defensively, Dallas was severely outmatched, allowing 33 points, including 20 in the fourth quarter, on 467 total yards. Dak Prescott led the Cowboys offense with 195 yards and one touchdown on 19 completions. CeeDee Lamb added a team-high seven catches for 58 yards.

Indianapolis Colts Preview

Daniel Jones leads the Indianapolis offense this season with 1,542 passing yards and five touchdowns on 162 completions, along with 75 rushing yards and one score on 25 carries. Jonathan Taylor is the top ball carrier on the roster with 610 yards and eight touchdowns on 148 carries. Seth McGowan has added 163 yards on 37 carries. Josh Downs leads the Indianapolis receiving corps with 330 yards and one touchdown on 30 catches. Keenan Allen has added 325 yards and one score on 36 receptions, while Tyler Warren has chipped in 231 yards and two touchdowns on 34 catches.

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Offensively, Indianapolis struggled a week ago, scoring just seven points on 243 total yards after committing three turnovers and converting only three third downs. Defensively, the Colts were obliterated, allowing 42 points, including 28 in the first half, on 366 total yards. Daniel Jones led Indianapolis with 144 passing yards and one touchdown on 19 completions. Keenan Allen was the top target with 67 yards on seven receptions.

Dallas Cowboys vs Indianapolis Colts Pick

Both teams have had their share of struggles this season, but Dallas is in the better position heading into Sunday. Look for the Cowboys to put it all together in this matchup and pick up a much-needed victory against a struggling Indianapolis team. Dallas should find success on both sides of the ball against a Colts team that has struggled throughout the year. Take the Cowboys to get the job done on the road, picking up the win and covering the spread for their fourth victory of the season.

  • Pick:
Dallas Cowboys -4.5
  • Secondary:
 Under 51.5

Final Score Prediction: Dallas Cowboys win and cover 24-13.

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