Green Bay Packers vs Detroit Lions Picks and Prediction for Thursday November 27 2025

By: Eddie Kline Published 11/24/2025, 10:01 PM ET

Packers Preview

In the first game of a Thanksgiving Day NFL tripleheader, the Green Bay Packers will invade Ford Field to take on the Green Bay Packers. Get ready for all the football action with our NFL Picks. The Packers (7-3-1) rank fourth in the league in total defense and are limiting opponents to 18.4 points per game. On Sunday, Green Bay forced three turnovers and registered five sacks during a 23-6 home victory versus Minnesota.

Green Bay RB Emanuel Wilson carried 28 times for 107 yards and two scores in place of injured RB Brandon Jacobs. Brandon McManus nailed three field goals and Micah Parsons had a pair of sacks. Christian Watson added a game-high 49 receiving yards for the Packers. The best sportsbooks are the best way to go when you are betting on the Packers.

Lions Preview

The Detroit Lions have won four of their first five home games and are looking to win their first Super Bowl title in franchise history. The Lions (7-4) rank fourth in the league in total offense and are averaging 29.6 points per contest. On Sunday, RB Jahmyr Gibbs scored a 69-yard touchdown on the first play in overtime to lift Detroit to a thrilling 34-27 home victory versus the New York Giants.

Gibbs finished with a career-high 219 rushing yards and caught 11 balls for 45 yards. Detroit K Jake Bates drilled a career-long 59-yard field goal with 28 seconds remaining in regulation to send the game to overtime. Amon-Ra St. Brown contributed nine receptions for a game-high 145 yards and a score. Make sure you know about how the fans are looking on prediction markets for the Lions with the Onyx Odds promo code.

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Packers vs Lions Pick

Green Bay played without WR Matthew Golden (shoulder/wrist), WR Jayden Reed (shoulder/foot), and RB Josh Jacobs (knee) on Sunday. Their status for this game is uncertain. The Lions were just gashed for 500 plus yards against the Giants and that does not bode well here. Take the Packers to win on the road. Final Score Prediction, Green Bay Packers win 27-23. Getting the most out of your bets on Pacers vs Lions can be done by using the Fanatics Sportsbook promo code.

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