Indianapolis Colts at Pittsburgh Steelers Picks and Prediction for Sunday, November 2, 2025
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The Indianapolis Colts visit the Pittsburgh Steelers on Sunday at Acrisure Stadium. Indianapolis is 7–1 (2–1 away) and on a four-game win streak after a 38–14 win over Tennessee. Pittsburgh is 4–3 (2–2 home) after falling 35–25 to Green Bay. Indianapolis is first in the AFC South, and Pittsburgh is third in the AFC North. Be ready for all the NFL action with our free NFL Picks.
Game Information for Colts vs Steelers
Date: Sunday, November 2
Time: 1:00 PM ET
Where: Acrisure Stadium, Pittsburgh, PA
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TV: CBS
Indianapolis Colts Preview
Indianapolis averages 34.6 points per game, third in the league. Daniel Jones has thrown for 2,062 yards with 13 touchdowns and 3 interceptions, completing 71.2% of his passes. Jonathan Taylor leads the rushing attack with 850 yards and 12 touchdowns, averaging 5.9 yards per carry. Tight end Tyler Warren leads the team with 492 receiving yards and 3 touchdowns, while Michael Pittman Jr. has six scores.
Defensively, the Colts allow 20 points per game and have forced seven turnovers during their four-game win streak. DeForest Buckner leads the Colts with 4 sacks, and safety Nick Cross has a team-high 56 tackles. Indianapolis has scored at least 31 points in four straight games while holding opponents under 21 in each.
Pittsburgh Steelers Preview
Pittsburgh averages 24.3 points per game and gives up 24.0. Aaron Rodgers has 1,489 passing yards with 16 touchdowns and 5 interceptions, completing 68.3% of his throws. Jaylen Warren leads the running game with 373 yards, while DK Metcalf has 461 receiving yards and 5 touchdowns. Tight end Pat Freiermuth adds 200 yards and two scores as a steady option over the middle.
The defense has been up and down. Linebacker Payton Wilson leads with 57 tackles, Nick Herbig has 4.5 sacks, and T.J. Watt has 4.0. Pittsburgh has only two takeaways in its last three games and has allowed 11 passing touchdowns this season. The Steelers have been better at home, winning two of four at Acrisure Stadium.
Indianapolis Colts at Pittsburgh Steelers Prediction
Indianapolis is the more balanced team on both sides of the ball. The Colts’ running game with Taylor and a solid passing effort from Jones will control possession. Pittsburgh’s offense has been inconsistent, and its defense has struggled against play-action looks. Final Score Prediction: Indianapolis Colts win and cover ATS 31-21.
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