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Indianapolis Colts vs Seattle Seahawks Picks and Predictions for Saturday, December 13, 2025

By: Cameron Ross Published 12/13/2025, 10:47 PM ET

Indianapolis Colts vs Seattle Seahawks Game Information

The Indianapolis Colts will be on the road Sunday afternoon for a 4:25 PM matchup in Seattle against the Seattle Seahawks. The Colts have eight wins and five losses this season, but have lost 4 of their last 5, including a 17-point road loss to Jacksonville a week ago. The Seattle Seahawks return home this week with ten wins and three losses, having won four of the previous five, including three in a row, after a 28-point blowout victory on the road in Atlanta. Stay in the action with our NFL Picks.

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Indianapolis Colts Preview

Daniel Jones has led the Indianapolis offense this season with 3101 yards and 19 touchdowns on 261 completions. Jonathan Taylor is the top ball carrier on the team with 1356 yards and 16 scores on 247 carries. Alec Pierce leads all receivers with 769 yards and two touchdowns on 38 receptions. Michael Pittman Jr. has 699 yards and seven scores on 69 grabs this season.

Seattle Seahawks Preview

Sam Darnold leads the Seattle offense this season with 3162 yards and 22 touchdowns on 241 completions. Kenneth Walker III leads the way on the ground for Seattle with 762 yards and four touchdowns on 170 carries, while Zach Charbonnet has chipped in 483 yards and eight scores on 132 carries. Jaxon Smith-Njigba leads the team with 1428 yards and 9 touchdowns on 89 receptions.

Indianapolis Colts vs Seattle Seahawks Prediction

Indianapolis got off to a hot start this season, but has floundered over the last few weeks. Look for Seattle to continue their winning ways Sunday afternoon as it rolls to another victory. Take the Seahawks to do the work on both sides of the ball as they overwhelm Indianapolis for 60 minutes, leading to the win and cover at home. Final Score Prediction, Seattle Seahawks win and cover 27-7. Make sure you know about how the fans are looking on prediction markets for the Colts with the Fliff promo code. The best sportsbooks are the best way to go when you are betting on the Seahawks. Make sure when you place your Colts vs Seahawks bet you are using the bet365 bonus code.

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Colts vs Seahawks Best Picks

  • Seattle Seahawks -3.5
  • Under 41.5
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