Jacksonville Jaguars vs Cincinnati Bengals Picks and Predictions for Sunday, September 14, 2025
The AFC clash takes play at Paycor Stadium on Sunday when the Jacksonville Jaguars visit the Cincinnati Bengals. Cincinnati is favored by -3.5 with the total at 50.5. Cincinnati is coming off a 17-16 win at Cleveland, while Jacksonville handled Carolina 26-10. Kickoff is set for 1:00 PM ET on CBS with the weather around 80 degrees. Get our winning NFL predictions.
Jacksonville Jaguars Preview
Jacksonville leaned heavily on Travis Etienne Jr. in the opening game. Etienne Jr gained 143 yards on 16 carries, including a 71-yard burst. Trevor Lawrence went 19-of-31 for 178 yards with one touchdown and one interception, with Brenton Strange (59 yards) and Dyami Brown (52 yards) as Lawrence’s favorite targets. The offense put up 200 rushing yards, showing a commitment to the ground attack. Defensively, Foyesade Oluokun posted 10 tackles, and Jourdan Lewis added an interception as the defense controlled the middle of the field.
The Jaguars’ ability to generate big plays on the ground is their biggest asset. Lawrence wasn’t pressured often in Week 1, but facing Cincinnati’s front will be tougher, particularly if the Jaguars cannot establish a running game early. Special teams also provided a boost, with Cam Little making all four of his field goals. Protecting Lawrence from unnecessary hits while staying balanced is the Jaguars ' formula to win on the road.
Cincinnati Bengals Preview
Cincinnati relied on its defense in the opener, holding Cleveland to 16 points. Joe Burrow finished 14-of-23 for 113 yards and a touchdown, connecting with Noah Fant on the score while Tee Higgins caught three passes for 33 yards. However, Burrow was sacked three times. Chase Brown was busy with 21 carries but managed only 43 yards, highlighting the need for more production on the ground. Defensively, Jordan Battle had 12 tackles and an interception, and Trey Hendrickson added a sack.
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The Bengals’ passing game should be sharper this week at home. Higgins and Ja’Marr Chase were quiet, but Burrow is unlikely to stay conservative two games in a row. If the offensive line holds better, Cincinnati’s vertical game can finally open up. The defense is in rhythm, with 95 combined tackles and two sacks last week, showing strong tackling and pressure on the opposing QB.
Jacksonville Jaguars vs Cincinnati Bengals Prediction
Burrow will improve Cincinnati’s passing game against Jacksonville, and Cincinnati’s defense tends to bend but doesn’t break, thus it will not give up big chunks of yards on the ground or through the air to the Jaguars. Jacksonville will keep it close, but Cincinnati’s offense down the stretch will secure a win and cover. Final Score Prediction: Cincinnati Bengals win and cover ATS 27-20.
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Best Picks
- Cincinnati Bengals -3.5
- Under 50.5
