Las Vegas Raiders vs Los Angeles Chargers Picks, Prediction, Odds, and Line Movement for Sunday September 20 2026
It's safe to say Jim Harbaugh does not plan on allowing any 63-21 results any time soon, and that history looms large over these Raiders vs Chargers picks this week. Since the Raiders famously crushed the Chargers in December 2023, Los Angeles has won and covered each of the last four meetings with all four victories coming by double digits. For more matchups this week, check out our full slate of NFL picks before placing a wager.
TLDR: Quick Picks and Prediction
- Spread Pick: Los Angeles Chargers -6.5
- Total Pick: Over 43.5
- Projected Final Score: Chargers 30, Raiders 17
Odds and Line Movement
Current Odds
| Market | Line | Public Betting ($, #) |
|---|---|---|
| Spread (Las Vegas / L.A. Chargers) | LV +6.5 (-105) / LAC -6.5 (-115) | LAC 70%, LV 55% |
| Total (Over / Under) | Over 43.5 (-110) / Under 43.5 (-110) | UN 100%, UN 80% |
Line Movement - Spread
| Date | Las Vegas | L.A. Chargers | Public Betting ($, #) |
|---|---|---|---|
| 09/15 | +6.5 (-105) | -6.5 (-115) | LAC 70%, LV 55% |
| 09/15 | +6.5 (-102) | -6.5 (-120) | LAC 70%, LV 55% |
| 09/14 | +7 (-108) | -7 (-112) | LAC 87%, LV 56% |
| 09/13 | +7 (-110) | -7 (-110) | LV 58%, LAC 75% |
| 09/13 | +7.5 (-122) | -7.5 (+100) | LV 58%, LAC 75% |
| 09/13 | +7.5 (-112) | -7.5 (-108) | LV 58%, LAC 75% |
| 09/13 | +7.5 (-118) | -7.5 (-104) | LV 51%, LAC 67% |
| 09/13 | +7.5 (-115) | -7.5 (-105) | LV 100%, LV 100% |
| 09/13 | +8.5 (-115) | -8.5 (-115) | LV 100%, LV 100% |
Line Movement - Total
| Date | Over | Under | Public Betting ($, #) |
|---|---|---|---|
| 09/14 | 43.5 (-110) | 43.5 (-110) | UN 100%, UN 80% |
| 09/14 | 43.5 (-115) | 43.5 (-105) | UN 100%, UN 100% |
| 09/14 | 43.5 (-112) | 43.5 (-108) | UN 100%, UN 100% |
| 09/14 | 43.5 (-110) | 43.5 (-110) | UN 100%, UN 100% |
| 09/13 | 44.5 (-105) | 44.5 (-115) | N/A |
| 09/12 | 42.5 (-105) | 42.5 (-115) | N/A |
| 09/09 | 42.5 (-105) | 42.5 (-115) | N/A |
| 09/08 | 42.5 (-118) | 42.5 (-104) | N/A |
Raiders vs Chargers Key Matchups and Game Preview
Raiders Get Kubiak Era Off to Good Start
Welcome to Raider Nation, Klint Kubiak. The former offensive coordinator earned his first win as a head coach as Las Vegas handled Miami with relative ease. Kirk Cousins went 21-of-30 with three touchdowns and two interceptions in his debut in silver-and-black, giving the Kubiak era an encouraging opening chapter.
Las Vegas Finds Life Under New Staff
Over the last few years, Kubiak has developed a knack for running some really strong offenses behind middle-of-the-road quarterbacks. Since 2022, the quarterbacks Kubiak has worked with include Russell Wilson, Brock Purdy, Derek Carr and Sam Darnold. Solid? Absolutely. Flashy? Not so much. There is real trust that Kubiak and Cousins will hold up their end of the deal when it comes to this total.
LAC Defense Adjusts Without Minter
The Chargers' loss to Arizona in Week 1 had more to do with the Cardinals' improvement than any failure on Los Angeles' part. Arizona's biggest problems last year revolved around injuries and depth, issues that typically are not a factor in Week 1, and the Cardinals showed what they are capable of with a new coaching staff and a clean bill of health.
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Chargers Own Recent Series History
Jim Harbaugh's squad deserves a small pass for that Week 1 result, but it is worth wondering how much he misses now-Ravens head coach Jesse Minter, who worked as Harbaugh's defensive coordinator over the last four seasons. In their first game without Minter, the Chargers' defense allowed Arizona to score 26 points with 393 total yards and 23 first downs on 5.5 yards per play, a number Arizona only hit three times in 17 games last year.
Raiders Total Looks Live
Justin Herbert should look a little more comfortable against a defense he has crushed in the past. In two games against the Raiders, Herbert completed 72.3 percent of his passes while averaging 8.4 yards per attempt with four touchdowns and one interception. That Raiders-Dolphins game had 37 points at the midway point of the third quarter, but no one found the end zone over the final 25 minutes, and it would be surprising if that happened again in a game involving these AFC West rivals.
Betting Trends: LV vs LAC
- Los Angeles has won and covered each of the last four meetings against Las Vegas, all by double digits.
- Kirk Cousins threw for three touchdowns and two interceptions while completing 21 of 30 passes in his Raiders debut.
- The Chargers allowed Arizona to score 26 points on 393 total yards and 23 first downs in their first game without former defensive coordinator Jesse Minter.
- Justin Herbert has completed 72.3 percent of his passes against the Raiders over his last two meetings, averaging 8.4 yards per attempt with four touchdowns and one interception.
- The spread has moved from Las Vegas +8.5 on September 13 down to Las Vegas +6.5 currently.
- The total has climbed from 42.5 up to 44.5 before settling at 43.5, with public money now leaning Under.
Key Injuries and Things To Know: LV and LAC
- Kirk Cousins threw two interceptions in his Raiders debut despite three touchdown passes.
- Klint Kubiak has a track record of running effective offenses with veteran quarterbacks such as Russell Wilson, Brock Purdy, Derek Carr and Sam Darnold since 2022.
- The Chargers are adjusting to life without former defensive coordinator Jesse Minter, who departed for Baltimore.
- Los Angeles allowed 393 total yards and 23 first downs to Arizona in Week 1.
- Justin Herbert has historically thrived against the Raiders, posting strong efficiency numbers in recent meetings.
Raiders vs Chargers Side and Over/Under Picks
- Spread: Los Angeles Chargers -6.5
- Total: Over 43.5
Los Angeles has dominated this series recently, and Justin Herbert's track record against the Raiders makes it hard to fade the Chargers even after a Week 1 loss that owed more to Arizona's improvement than any real issues in Los Angeles. On the total, Klint Kubiak's history of running efficient offenses with capable quarterbacks like Kirk Cousins, combined with a Chargers defense breaking in life without Jesse Minter, supports leaning toward the Over.
Final Score Prediction
- Los Angeles Chargers: 30
- Las Vegas Raiders: 17
Expect Justin Herbert to continue his strong run against Las Vegas while Kirk Cousins and the Raiders offense keep this one moving enough to clear the total.
How to Wager On Raiders vs Chargers
Bettors looking to shop for the best number on Raiders vs Chargers have several tools available before placing a wager. Comparing the spread and total across multiple sportsbooks can help secure better value than settling for a single closing line, especially with a total that has moved a couple of points throughout the week. For those who want an extra layer of analysis before betting this AFC West matchup, our AI picks breakdown is a useful starting point. Bettors can also dig deeper with our Dimers review and Oddible review to see how different models project this matchup before locking in a side, total, or player prop.
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