Los Angeles Rams at Jacksonville Jaguars Picks and Predictions for Sunday, October 19, 2025
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The Los Angeles Rams visit the Jacksonville Jaguars at Wembley Stadium on Sunday at 9:30 a.m. ET on NFL Network. The Rams defeated the Ravens 17–3 last week and are 4–2, second in the NFC West. The Jaguars lost to the Seahawks 20–12 and are 4–2, second in the AFC South. Join a passionate community of fans who rely on our data-driven free NFL picks to secure their victories.
Los Angeles Rams Preview
Matthew Stafford has thrown for 1,684 yards with 12 touchdowns and 2 interceptions, guiding a balanced offense through six games. Kyren Williams leads the ground game with 418 rushing yards and 2 touchdowns, while Puka Nacua (questionable) is the top receiver with 616 yards on 54 catches. Davante Adams has added 396 yards and 3 touchdowns, giving Stafford another talented target to throw to.
On defense, Byron Young leads with 7.5 sacks, Kam Curl has 2 interceptions, and Nate Landman tops the team with 58 tackles. The Rams have been strong against the pass and generated steady pressure up front. If Nacua plays, Los Angeles can stretch the field while using Williams to control tempo and protect Stafford.
Jacksonville Jaguars Preview
Trevor Lawrence has passed for 1,324 yards, 8 touchdowns, and 5 interceptions through six games. Travis Etienne Jr. leads the running game with 470 yards and 2 scores, while Brian Thomas Jr. has 334 receiving yards on 24 catches to pace the receivers. Parker Washington and Dyami Brown give Lawrence additional targets for the short passing attack.
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Defensively, Foyesade Oluokun leads the Jaguars with 53 tackles, Devin Lloyd has 4 interceptions, and Arik Armstead has 3.5 sacks. Jacksonville’s defense thrives on turnovers but has struggled with consistency against the run. To keep pace with the Rams, the Jaguars will need Lawrence to avoid throwing interceptions and strong production from Etienne to stay balanced on offense.
Los Angeles Rams vs Jacksonville Jaguars Prediction
Los Angeles brings the more complete roster to London. Stafford’s accuracy and the Rams’ pass rush give them the advantage, while Jacksonville’s offense remains up-and-down behind an offensive line that has allowed pressure too often. Expect the Rams to control the line of scrimmage and make enough plays through the air to win. Final Score Prediction: Los Angeles Rams win and cover ATS 27–21.
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Best Picks
- Los Angeles Rams -3
- Over 45.5
- Davante Adams anytime touchdown
