Los Angeles Rams vs Arizona Cardinals Picks and Predictions for Sunday, November 15, 2026

By: David Anicetti Published 11/11/2026, 08:55 PM ET
LA Rams RB Kyren Williams rushing against Washington

The Los Angeles Rams (5-4), T-2nd NFC West) pay a visit to the desert southwest on Sunday to play the Arizona Cardinals 3-6, 4th NFC West). The opening kickoff at State Farm Stadium is at 5:05 pm ET, and CBS will cover the game. Los Angeles defeated Washington 20-13 last Sunday while Arizona fell to Seattle, 17-3. Los Angeles is favored at -9.5, and the over/under total sits at 40.5. Cash in big with our free NFL picks.

Los Angeles Rams Team Preview - Recent Form and Key Players

Three wins in a row have put Los Angeles above .500. Puka Nacua caught 14 passes for 150 yards and a touchdown against Washington, while Matthew Stafford threw for 219 yards. Myles Garrett returned from injury with three sacks. The Rams previously beat the Chargers 24-9 and Raiders 35-21.

Now Stafford faces a tougher job. Nacua suffered knee and foot injuries late against Washington and could miss at least a month. Davante Adams is also on injured reserve. Stafford has 2,374 passing yards, 16 touchdowns and nine interceptions. Kyren Williams has rushed for 593 yards and six scores, with Blake Corum adding 447 yards.

Los Angeles Team Stats:

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  • Points per game: 23.8
  • Passing yards: 2,387
  • Rushing yards: 1,128
  • Rushing touchdowns: 11
  • Defensive interceptions: 7

Injuries: Nacua is doubtful. Jordan Whittington, Trent McDuffie and Joe Cardona are questionable. Terrance Ferguson is designated to return from injured reserve.

Arizona Cardinals Team Preview - Recent Form and Key Players

The Cardinals came away with just three points in Sunday's 17-3 loss to Seattle. Chad Ryland opened the scoring with a 28-yard field goal, but Arizona couldn't find the end zone the rest of the afternoon. Gardner Minshew finished with 166 passing yards, and a fourth-down attempt from Seattle's 2-yard line fell incomplete. Arizona has dropped three of its last four games, with its 18-16 victory over the Rams being the lone win during that stretch.

Minshew's elbow injury leaves Arizona with another concern heading into Sunday. He's listed as doubtful after completing 38 of 53 passes for 354 yards and three touchdowns in two games. On the ground, Tyler Allgeier has carried 89 times for 369 yards and two touchdowns. Trey McBride remains Arizona's top receiving target with 73 receptions, 598 yards and five scores. Michael Wilson follows with 51 catches for 546 yards.

Arizona Team Stats:

  • Points per game: 19.8
  • Passing yards: 2,080
  • Rushing yards: 924
  • Rushing touchdowns: 4
  • Defensive sacks: 19

Injuries: Minshew is doubtful. Jayden Williams, Bam Knight, Jon Gaines II and Hjalte Froholdt are questionable.

Los Angeles Rams vs Arizona Cardinals Prediction

The Rams have won three straight, holding Washington to 13 points and the Chargers to nine in their last two outings. Arizona managed only three points against Seattle, though the Cardinals did beat Los Angeles earlier this season. With Nacua and Adams sidelined, Stafford will need more help from the running game. Williams and Corum have combined for 1,040 rushing yards this season, giving Los Angeles another way to move the ball.

Final Score Prediction: Los Angeles 24-13.

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  • Los Angeles Rams -9.5
  • Under 40.5
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