New Orleans Saints vs Los Angeles Rams Picks and Predictions for Saturday, August 22nd, 2026

By: Cameron Ross Published 08/21/2026, 08:22 PM ET

Saints vs Rams Game Information

The New Orleans Saints will be on the road for the first time in the preseason Saturday with a 4:00 PM matchup inside SoFi Stadium in Inglewood for a game against the Los Angeles Rams. New Orleans is winless in the preseason coming into Game 2 on Saturday following a 4-point home loss to Jacksonville last week. The Los Angeles Rams will be at home for the first time in the preseason undefeated following their 8-point road victory against Kansas City last time out. Stay in the news with our NFL Picks.

Saints Preview

Zach Wilson led the show for the New Orleans offense last week, completing 11 passes for 145 yards and 1 score. Hunter Dekkens completed 8 passes for 69 yards, and Spencer Rattler compiled 42 yards on 8 completions. Audric Estime led the way on the ground for New Orleans with 28 yards and 1 score on 5 carries. Bub Means was the top receiver on the team with 77 yards on 4 catches, while Barion Brown had 53 yards on 4 receptions. Oscar Delp chipped in 10 yards and 1 score on 3 grabs.

Rams  Preview

Ty Simpson led Los Angeles last week, completing 21 passes for 190 yards and 2 scores, while Stetson Bennett completed 4 passes for 38 yards. Jordan Waters led the team on the ground with 37 yards on 5 carries. Brennan Presley led Los Angeles for 58 yards on 4 receptions. Mark Redmond chipped in heavily with 47 yards on 3 catches. Dean Connors added 4 catches for 29 yards and 2 scores last week.

Saints vs Rams  Pick

The Rams were the better team in Week 1 of the preseason, and that will carry over into Saturday. Look for Los Angeles to continue to click on all cylinders against a below-average New Orleans team. Take the Rams to remain undefeated in the preseason Saturday as they get the win and cover at home

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  • Pick: Los Angeles Rams +1.5
  • Secondary:  Over 37.5

Final Score Prediction: Los Angeles Rams win 28-17

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