Pittsburgh Steelers vs Buffalo Bills Picks and Prediction for Thursday August 27 2026

By: Eddie Kline Published 08/25/2026, 07:47 PM ET

Steelers Preview

The week three NFL preseason will kick off on Thursday night, when the Pittsburgh Steelers battle the Buffalo Bills from Highmark Stadium. Get ready for all the football action with our NFL Picks.The Steelers (10-7)  have reached the playoffs in five of the last six seasons, but have not won a single playoff game during that stretch. Pittsburgh moved on from veteran head coach Mike Tomlin in the offseason and reunited QB Aaron Rodgers with former Green Bay head coach Mike McCarthy. The Steelers traded for WR Michael Pittman Jr. and that will give Rodgers a nice complement to WR D.K. Metcalf. 

On Friday, Pittsburgh managed just 242 total yards and committed a pair of turnovers during a 17-0 home loss versus the New York Jets. Rodgers did not see the field, but rookie QB Drew Allar completed 11 of 23 passes for a game-high 110 yards. 

Bills Preview

The Buffalo Bills have won at least ten games in seven consecutive seasons and are in search of their first Super Bowl title in franchise history. The Bills (12-5) finished fourth in the NFL in total offense and averaged 28.3 points per game. With QB Josh Allen (25 pass TDs) driving the bus and newly acquired WR D.J. Moore in the fold, Buffalo should remain a top-five offensive attack. RB James Cook III rushed for a career-best 1,621 yards and found the end zone 14 times in 2025. 

On Saturday, Buffalo forced two turnovers and held Cleveland scoreless over the final three quarters to earn a 31-7 road triumph. QB Shane Buechele threw for a touchdown and added another score on the ground for the Bills, who outgained the Browns by a sizable 368-194 margin.  

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Steelers vs Bills Pick

Buffalo WR Khalil Shakir missed the last game with an undisclosed injury and is listed as questionable for this contest. Pittsburgh head coach Mike McCarthy is 5-10 ATS in the preseason over the last four years. Take the Bills to finish the preseason slate with their third consecutive double-digit victory. Final Score Prediction, Buffalo Bills win 24-11. 

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