Pittsburgh Steelers vs New England Patriots Picks, Prediction, Odds, and Line Movement for Sunday September 20 2026

By: Kyle Kargel Published 09/18/2026, 11:59 AM ET
Steelers vs Patriots picks

In a game that Drake Maye would love to forget, the Steelers beat the Patriots 21-14 in Foxboro last season, and that late-game heartbreak is worth remembering for anyone considering Steelers vs Patriots picks this week. New England's Week 1 struggles against Seattle looked all too familiar, while Pittsburgh was far from impressive in a narrow win over Atlanta. For more matchups this week, check out our full slate of NFL picks before placing a wager.

TLDR: Quick Picks and Prediction

  • Spread Pick: New England Patriots -4.5
  • Total Pick: Under 41.5
  • Projected Final Score: Patriots 20, Steelers 13

Odds and Line Movement

Current Odds

Market Line Public Betting ($, #)
Spread (Pittsburgh / New England) PIT +4.5 (-102) / NE -4.5 (-120) NE 96%, NE 70%
Total (Over / Under) Over 41.5 (-110) / Under 41.5 (-110) UN 91%, UN 63%

Line Movement - Spread

Date Pittsburgh New England Public Betting ($, #)
09/15 +4.5 (-102) -4.5 (-120) NE 96%, NE 70%
09/13 +4.5 (-104) -4.5 (-118) NE 99%, NE 67%
09/08 +5.5 (-110) -5.5 (-110) PIT 100%, PIT 100%

Line Movement - Total

Date Over Under Public Betting ($, #)
09/16 41.5 (-110) 41.5 (-110) UN 91%, UN 63%
09/16 41.5 (-115) 41.5 (-105) UN 91%, UN 63%
09/16 41.5 (-114) 41.5 (-106) UN 91%, UN 63%
09/16 41.5 (-102) 41.5 (-120) UN 91%, UN 63%
09/15 42.5 (-102) 42.5 (-120) UN 91%, UN 65%
09/15 42.5 (-104) 42.5 (-118) UN 91%, UN 65%
09/14 42.5 (-105) 42.5 (-115) UN 74%, UN 57%
09/14 42.5 (-106) 42.5 (-114) UN 65%, UN 67%
09/14 42.5 (-105) 42.5 (-115) UN 65%, UN 67%
09/13 42.5 (-118) 42.5 (-104) OV 100%, OV 100%
09/13 43.5 (-104) 43.5 (-118) OV 100%, OV 100%
09/08 43.5 (-105) 43.5 (-115) N/A

Steelers vs Patriots Key Matchups and Game Preview

Patriots Search for Answers After Seattle Loss

The Patriots' 2026 season began in a very similar fashion to how the 2025 season ended. Drake Maye was never able to get comfortable against the Seahawks' defense, ending the night with three interceptions and three sacks as New England failed to take advantage of Sam Darnold's absence on the other side. In a game Maye would love to forget, this matchup also carries the memory of last season's 21-14 loss in Foxboro, where New England was outgained 369-203 by Pittsburgh yet still found a way to lose.

New England's Offense Missing Key Pieces

Maye's struggles will draw most of the headlines, but he did not receive much help. Newly acquired receiver AJ Brown suffered an ankle injury and will miss the next four games. Dynamic running back TreVeyon Henderson missed the Week 1 contest, and Rhamondre Stevenson, who averaged just 2.8 yards per carry, was not able to fill the void in production. Per NFL analyst Kevin Cole from Unexpected Points, five of Stevenson's 18 carries resulted in a significant loss of momentum, including a failure to pick up a 3rd-and-1.

PIT Struggles Against Backup QB

Pittsburgh earned a 20-13 win over Atlanta that was probably closer than it should have been. The Steelers' offense only generated one touchdown and 264 total yards on 4.1 yards per play. Pittsburgh went 3-of-13 on third down and 0-for-2 on fourth down with a lost fumble and a missed field goal, all against a Falcons team that was starting its third option at quarterback.

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Steelers Offense Stalls Against Atlanta

Former Packer Romeo Doubs has seemingly failed to gain the confidence of Maye. Doubs failed to catch any of his three targets, including a costly drop when he was wide open with under ten minutes remaining in the fourth quarter. That kind of missed opportunity compounds the issues New England is already dealing with at the skill positions.

Patriots Get Extra Time to Prepare

With New England having three extra days to prepare for life without Brown, there is reason to lean in the Patriots' direction. If Henderson can return to the Patriots' offense, that gives Maye a valuable option he was sorely lacking against the Seahawks, and Pittsburgh's uninspiring performance against a Falcons team starting its third-string quarterback does little to instill confidence heading into this one.

  • Pittsburgh beat New England 21-14 last season despite being outgained 369-203 in total yardage.
  • Five of the last six meetings between the Steelers and Patriots have stayed under the total, averaging 36.5 points per game.
  • Drake Maye threw three interceptions and was sacked three times in New England's Week 1 loss to Seattle.
  • Pittsburgh managed just one offensive touchdown and 264 total yards in a 20-13 win over Atlanta.
  • The Steelers went 3-of-13 on third down and 0-for-2 on fourth down in that Week 1 win.
  • The spread has moved from New England -5.5 on September 8 to New England -4.5 currently.
  • The total has fallen from 43.5 down to 41.5 over the course of the week, with heavy public backing on the Under.

Key Injuries and Things To Know: PIT and NE

  • AJ Brown suffered an ankle injury in Week 1 and will miss the next four games for New England.
  • TreVeyon Henderson missed New England's Week 1 game and his potential return is a key storyline this week.
  • Rhamondre Stevenson averaged just 2.8 yards per carry in Week 1, with five of his 18 carries resulting in a significant loss of momentum.
  • Romeo Doubs failed to catch any of his three targets in Week 1, including a costly drop late in the fourth quarter.
  • Pittsburgh's offense was held to one touchdown and committed a lost fumble and a missed field goal against Atlanta.

Steelers vs Patriots Side and Over/Under Picks

  • Spread: New England Patriots -4.5
  • Total: Under 41.5

New England's extra days of preparation and the potential return of TreVeyon Henderson give Drake Maye more to work with after a rough Week 1 outing. Pittsburgh, meanwhile, struggled to move the ball against a Falcons team starting its third-string quarterback, which does not inspire much confidence against a Patriots defense that will be well-rested. On the total, five of the last six meetings between these two teams have gone under, averaging 36.5 points per game, well below the current number of 41.5.

Final Score Prediction

  • New England Patriots: 20
  • Pittsburgh Steelers: 13

Expect New England to bounce back behind extra rest and a potentially improved backfield, while Pittsburgh's offensive struggles carry over from a shaky Week 1 performance against Atlanta.

How to Wager On Steelers vs Patriots

Bettors looking to shop for the best number on Steelers vs Patriots have several tools available before placing a wager. Comparing the spread and total across multiple sportsbooks can help secure better value than settling for a single closing line, especially with a total that has moved several points throughout the week. For those who want an extra layer of analysis before betting this matchup, our AI picks breakdown is a useful starting point. Bettors can also dig deeper with our Dimers review and Oddible review to see how different models project this matchup before locking in a side, total, or player prop.

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