San Francisco 49ers vs Las Vegas Raiders Picks and Predictions for Thursday, August 27th, 2026

By: Cameron Ross Published 08/27/2026, 12:08 AM ET

49ers vs Raiders Game Information

The San Francisco 49ers will be on the road Thursday night for an 8:00 PM matchup inside Allegiant Stadium in Las Vegas, NV, against the Las Vegas Raiders. San Francisco has split their first 2 games of the preseason coming into this matchup following a 24-point victory against the Los Angeles Chargers in their last outing. The Las Vegas Raiders will be back at home Thursday night with 1 win and 1 loss in the preseason after a 2-point road victory against Houston last week. Stay in the news with our NFL Picks.

49ers Preview

Mac Jones led the way for the 49ers offense last week, completing 6 passes for 89 yards in the game. Adrian Martinez completed 8 passes for 57 yards and 1 score, and Brock Purdy completed 4 passes for 29 yards. Sincere McCormick led the way on the ground for San Francisco with 53 yards and 1 score on 6 carries. Kaelon Black added a 2nd best 33 yards on 8 carries in the game. Khalil Martinez added 17 yards and 1 score on 4 carries, and quarterback Adrian Martinez chipped in 10 yards for 1 touchdown on 4 carries. KhaDarel Hodge led the way for the San Francisco 49ers last week with 46 yards on 4 grabs, and Jordan Watkins chipped in 3 catches for 41 yards.

Raiders Preview

Aidan O’Connell led the way for the Las Vegas offense last week, completing 15 passes for 166 yards. Recent number 1 overall pick Fernando Mendoza completed 8 passes for 86 yards in the game. Mike Washington Jr. was the top ball carrier on the team with 56 yards on 9 carries. Dylan Laube chipped in 37 yards and 1 score on 6 carries, and Dare Ogunbowale had 35 yards and 1 touchdown on 4 carries. Brandon Johnson was the top receiver in the game with 41 yards on 2 catches.

49ers vs Raiders Pick

Both teams have been shaky in the preseason so far, but Las Vegas will have the edge on Thursday. The Raiders will be at home and will likely be the healthier team. Take Las Vegas to do the job Thursday night as they get their second victory in a row with a win and cover at home against San Francisco.

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  • Pick: Las Vegas Raiders -3
  • Secondary:  Under 38.5

Final Score Prediction: Las Vegas Raiders win 21-13.

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