Seattle Seahawks at Jacksonville Jaguars Picks and Predictions for Sunday, October 12, 2025

By: David Anicetti Updated 10/10/2025, 11:49 PM ET
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The Seattle Seahawks visit the Jacksonville Jaguars on Sunday at EverBank Stadium with the opening kickoff at 1:oo PM ET on FOX. Seattle is 3–2 after a 38–35 loss to Tampa Bay and is 2–0 on the road. Jacksonville is 4–1 after a 31–28 win over Kansas City and is 3–0 at home. Current odds: Jaguars -1.5 and total 46.5 (opened 44.5). Experience the thrill of confident decision-making with our proven methods for selecting top free NFL picks.

Seattle Seahawks Preview

Sam Darnold is off to a strong start with 1,246 passing yards, 9 touchdowns, 3 interceptions, and a 73% completion rate. Jaxon Smith-Njigba leads all receivers with 34 catches for 534 yards and 2 scores. AJ Barner has 4 touchdown grabs and Tory Horton has 3, giving Darnold plenty of options. Kenneth Walker III has 330 yards on 68 carries with 3 touchdowns, and Seattle has topped 30 points in two of the last three.

On defense, Ernest Jones IV has 40 tackles. Leonard Williams and Byron Murphy II share the team lead with 2.5 sacks, and Coby Bryant has 2 interceptions. The secondary has several players to watch on the injury report: Devon Witherspoon (knee), Julian Love (hamstring), and Riq Woolen (concussion). DeMarcus Lawrence (quad) and Derick Hall (oblique) are also listed as questionable.

Jacksonville Jaguars Preview

Quarterback Trevor Lawrence has thrown for 1,066 yards with 6 touchdowns and 5 interceptions. Brian Thomas Jr. leads in receiving yards with 244, while tight end Brenton Strange has 20 catches for 204 yards. Travis Etienne Jr. leads all rushers with 443 yards on 77 carries (5.8 yards per carry) and 2 touchdowns. The Jaguars' key to success on offense is big gains on first and second down, leaving short yardage conversions for third down..

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The defense has produced timely plays. Foyesade Oluokun leads with 44 tackles. Devin Lloyd has 4 interceptions, and Arik Armstead has 2.5 sacks. Jacksonville is 3-0 at home and has won close games late with big plays. Injury notes: Robert Hainsey (hamstring) and Brenton Strange (hip) are questionable. Travon Walker (wrist) and Wyatt Milum (knee) are listed as inactive.

Seattle Seahawks at Jacksonville Jaguars Pick

Seattle has a better receiving corps, but Jacksonville’s running game and short passes have helped to give the Jaguars shorter third downs. With Etienne picking up good yardage on first and second downs on the ground, the Jaguars can control the pace and keep Darnold off the field for long stretches. The Jaguars will win a close battle with late heroics by Lawrence. Final Score Prediction: Jacksonville Jaguars win and cover ATS 23-20.

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Best Picks

  • Jacksonville Jaguars -1
  • Under 44.5
  • Travis Etienne Jr. anytime touchdown
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