Indiana Fever vs Las Vegas Aces Picks and Predictions for Sunday, September 21, 2025

By: David Anicetti Published 09/20/2025, 03:32 PM ET

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The Indiana Fever visit the Las Vegas Aces for Game 1 of their best-of-five semifinal series on Sunday, September 21. Tip-off is set for 3:00 PM ET on ABC. The Fever come in after an 87-85 win over Atlanta to clinch their first-round series, while the Aces are coming off a 74-73 win against Seattle at home to clinch that series. Score the winning basket with our WNBA picks.

Indiana Fever Preview

The Fever have found their game at the right time, winning four of the last five. Kelsey Mitchell has been the spark, averaging more than 23 points in the postseason while shooting with confidence from outside. Aliyah Boston continues to control the paint, pulling down nearly 10 boards per game in the playoffs. Indiana’s defense has also stepped up, holding Atlanta to just 60 points in Game 2 of the first round before closing the series on the road.

Indiana’s talent on the bench has helped handle injuries. Odyssey Sims has filled a key role, running the offense and adding over five assists per game in the postseason. Natasha Howard adds scoring inside, giving the Fever a steady second option in the frontcourt. If Mitchell gets hot early, Indiana has the scoring power to keep pace with Las Vegas.

Las Vegas Aces Preview

The Aces survived a tough test in Seattle and now open at home, where they’ve been one of the league’s most dangerous teams over the final month. A’ja Wilson has been unstoppable, putting up nearly 30 points per game with strong rebounding and rim protection. Jackie Young has added consistent scoring on the perimeter, giving the Aces another go-to option.

Chelsea Gray’s playmaking continues to set the tone, with almost eight assists per game in the postseason. Las Vegas also has the edge in postseason experience, with Wilson, Gray, and Young all thriving under pressure. The Aces’ defense showed cracks against Seattle, but the offense remains tough to slow down both at home and on the road.

Indiana Fever vs Las Vegas Aces Prediction

The Fever enter with momentum, and Mitchell’s scoring gives them a shot, but the Aces’ firepower and home-court advantage make Las Vegas the safer pick in Game 1. Expect Wilson and Young to carry Las Vegas in an up-tempo start to this semifinal series.

Best Picks

Las Vegas Aces -9.5
Over 163.5 total points

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