American All-Stars vs National All-Stars Picks, Prediction, Odds, and Line Movement for Tuesday July 14 2026

By: Kyle Kargel Updated 07/14/2026, 08:02 AM ET
American All-Stars vs National All-Stars picks
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The American League and National League square off Tuesday night in the 96th MLB All-Star Game at Citizens Bank Park in Philadelphia, with first pitch scheduled for 8:00 p.m. ET. The National League is a -1.5 run-line favorite, the American League is available at +1.5, and the total is set at 7.5 runs, and bettors looking for more exhibition and regular-season angles should check out our full slate of MLB picks before placing a wager. Below is a complete breakdown of the odds movement, injury news, betting trends and our final picks for this year's Midsummer Classic.

TLDR: Quick Picks and Prediction

  • Run Line Pick: American League +1.5
  • Total Pick: Under 7.5
  • Final Score Prediction: National League 4, American League 3

Odds and Line Movement

Current Odds

Date Time American League National League Public ($, #)
07/13 05:49:21PM +116 -136 NL 55%, 63%

Line Movement - Moneyline

Date Time American League National League Public ($, #)
07/12 08:45:45PM +116 -136 N/A
07/12 08:56:10PM +120 -142 N/A
07/13 00:26:16AM +120 -142 AL 94%, 42%
07/13 07:58:06AM +120 -142 AL 67%, 36%
07/13 02:07:12PM +120 -142 NL 55%, 63%
07/13 05:49:21PM +116 -136 AL 60%, 44%

Line Movement - Total

Date Time Over Under Public ($, #)
07/12 08:45:45PM 7½ (-110) 7½ (-110) N/A
07/13 07:58:06AM 7½o (-118) 7½u (-104) O92%, NULL
07/13 04:10:19PM 7½o (-122) 7½u (+100) O94%, NULL
07/14 07:47:42AM 7½o (-124) 7½u (+102) O95%, NULL
07/14 07:50:30AM 8o (-105) 8u (-115) O95%, NULL

American League vs National League: Key Matchups and Game Preview

Dylan Cease gets the start for the AL after finishing the first half 6-4 with a 2.56 ERA, 1.13 WHIP and an American League-leading 148 strikeouts in only 98.1 innings. His swing-and-miss ability gives the AL an excellent opening weapon against a powerful National League order, but Cease also issued 44 walks, creating some risk against patient hitters such as Juan Soto and Freddie Freeman. Philadelphia left-hander Cristopher Sánchez starts for the NL in his home ballpark after going 11-4 with a 2.62 ERA, 1.19 WHIP and 144 strikeouts over 127.1 innings.

American League Lineup

The American League lineup brings considerable power, with Yordan Alvarez batting .318 with 31 home runs and 70 RBIs, Junior Caminero contributing 28 homers and 59 RBIs, and Shea Langeliers adding 21 home runs. Bo Bichette, Bobby Witt Jr., Riley Greene and Ernie Clement help provide contact and athleticism deeper in the order.

National League Lineup

The NL can counter with Kyle Schwarber's 32 home runs, Soto's .290 average and 21 homers, and CJ Abrams' combination of 20 home runs, 67 RBIs and 15 stolen bases. Andy Pages also supplies lower-order production with 17 homers and 66 RBIs.

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Bullpen Depth Behind the Starters

The AL can follow Cease with Joe Ryan, Drew Rasmussen, Michael Wacha and Ranger Suárez, while the NL can deploy Chris Sale, Jacob Misiorowski, Yoshinobu Yamamoto and an elite group of relievers. With pitchers likely working only one inning and hitters repeatedly facing fresh, high-end arms, sustained rallies should be uncommon.

The moneyline has tightened over the past two days, moving from American League +120 and National League -142 down to the current AL +116 and NL -136, with public betting money shifting from a heavy 94% on the American League early to a more balanced 60% on the AL at the current price. The total has climbed steadily from an opening of 7.5 to as high as 8, with the public consistently backing the over at 92% or better across every recorded line movement.

AL and NL Key Injuries and Things to Know

  • National League: Shohei Ohtani (left knee inflammation) - replaced
  • American League: Byron Buxton (right hip impingement) - replaced
  • American League: Nick Kurtz - replaced
  • National League: Chase Burns - replaced
  • National League: Paul Skenes - Replaced

Shohei Ohtani was replaced because of left knee inflammation, while Byron Buxton was replaced after aggravating a right hip impingement. Nick Kurtz and Chase Burns were also replaced, opening roster spots for Tristan Peters, Foster Griffin and Justin Wrobleski. Those absences remove dangerous power and quality pitching, but both staffs remain deep enough to create difficult matchups throughout the night.

American League vs National League Side and Over/Under Picks

  • Run Line Pick: American League +1.5
  • Total Pick: Under 7.5

The National League has the deeper overall pitching collection and home-field familiarity, but laying 1.5 runs is difficult in an exhibition that could remain close into the late innings. With pitchers limited to short outings and both bullpens stacked with high-end arms, the under also holds appeal in a game where sustained rallies figure to be uncommon.

Final Score Prediction: American League vs National League

  • Predicted Final Score: National League 4, American League 3

How to Wager on American League vs National League

Bettors considering American League +1.5, the under 7.5, or the 4-3 final score projection have several tools available to help sharpen their approach to the All-Star Game. Our AI picks hub compiles model-based projections that can offer another data point beyond traditional handicapping for a unique event like this. Two especially useful resources for this matchup include the Dimers review, which breaks down run-scoring projections for both the American League and National League, and the Oddible review, which tracks real-time line movement like the shifts documented above. Combining these tools with the injury news and betting trends outlined in this preview can help bettors build a stronger case before wagering on the American League vs National League All-Star Game.

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