Arizona Diamondbacks vs Houston Astros Picks and Predictions for Sunday, September 6th, 2026
Diamondbacks vs Astros Game Information
The Arizona Diamondbacks continue their road trip in Texas Sunday afternoon with a 2:10 PM matchup in Houston against the Houston Astros. Arizona is 7 games above .500 and currently the 2nd-place team in the National League West, having won 2 of the last 3 games. The Houston Astros stay home Sunday, 3 games above .500 as the top team in the American League West, following the loss on Saturday to end a 3-game winning streak. Stay in the action with our MLB Picks.
Diamondbacks Preview
Brandon Pfaadt got the start for Arizona on Saturday, giving up 3 runs on 7 hits across 6.1 innings of work. The Arizona bullpen was phenomenal as well, giving up no runs on 2 hits over the next 3.2 innings, as Jonathan Loaisiga got the win and Brandyn Garcia got the save. Arizona saw a balanced scoring attack, with 4 different players driving in 1 run each.
Astros Preview
Ethan Pecko got the start for Houston on Sunday, giving up 1 run on 5 hits through 4.1 innings of action. The Houston bullpen was shaky, giving up 3 runs on 3 hits over the final 5.2 innings, as Bryan King gave up 1 run on 1 hit, leading to the loss. Isaac Paredes led the Houston offense on Saturday with 2 hits to drive in all 3 runs.
Diamondbacks vs Astros Pitching Matchup
Eduardo Rodriguez will be on the mound Sunday for Arizona. Rodriguez has been excellent this season, posting a 14-5 record and a 2.59 ERA across 167 innings. Peter Lambert will start for Houston. Lambert is 8-7 with a 3.66 ERA across 132.2 innings.
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Diamondbacks vs Astros Pick
Arizona enters this matchup with the clear starting-pitching advantage. Rodriguez has been one of the most reliable arms in baseball this season and should limit a Houston lineup that has lacked consistency. Take the Diamondbacks to avoid the sweep and leave Houston with a victory Sunday afternoon as they continue their playoff push.
- Pick: Houston Astros -112
- Secondary: Over 8.5
- Lean: Jose Altuve Over 1.5 Bases
Final Score Prediction: Houston Astros win 6-4.
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