Arizona Diamondbacks vs Los Angeles Dodgers Picks and Prediction for Friday March 27 2026
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The Arizona Diamondbacks and Los Angeles Dodgers meet at Dodger Stadium in Los Angeles, California, on Friday, March 27, 2026, with first pitch scheduled for 10:10 PM. Television coverage for this matchup will be on MLB.TV and MLB Net. Los Angeles enters the game at 1-0 and Arizona comes in at 0-1. The Dodgers are listed at -207 on the opening moneyline and -219 on the listed moneyline, while the Diamondbacks are priced at +179. The total is set at 8.5, with the over listed at -110 on the opener and -112 on the listed number, while the under is -108. On the run line, Arizona is +1.5 at -112 and Los Angeles is -1.5 at -108. Be sure to check out our free MLB picks for more daily baseball action.
Previous Game Recap & Box Score
These teams are coming right back after the Dodgers opened the series with an 8-2 win over the Diamondbacks. Arizona kept the game scoreless through the first three innings before breaking through with two runs in the fourth, but Los Angeles responded with four runs in the fifth and then put the game away with another four-run burst in the seventh. The overall flow was one of a competitive game early that shifted firmly in the Dodgers’ direction once their offense found its big swings.
The box score showed Arizona finishing with 2 runs on 6 hits and no errors, while Los Angeles scored 8 runs on 10 hits and also played clean defensively. The Diamondbacks left only 2 runners on base and went 1-for-3 with runners in scoring position, but they simply did not create enough chances over the course of the game. The Dodgers left 8 runners on base and went 3-for-7 with runners in scoring position, which reflected a lineup that kept building pressure and eventually converted enough of those opportunities to separate on the scoreboard.
Arizona’s offense leaned heavily on Geraldo Perdomo, who went 2-for-4 with a home run and both RBI in the loss. Corbin Carroll also scored a run, while Jordan Lawlar doubled and picked up a hit. Nolan Arenado and T. Tawa each added a hit, but the lineup as a whole struck out 8 times and did not get much sustained production beyond Perdomo’s fourth-inning homer. That one swing briefly gave Arizona life, but the offense could not add on after that moment.
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Los Angeles had much better balance at the plate. Will Smith went 2-for-4 with a home run and 3 RBI, while Andy Pages also homered and drove in 3 runs in a 2-for-4 night. Kyle Tucker and Mookie Betts each drove in a run, and Max Muncy reached base three times with a hit and two walks. Shohei Ohtani scored a run and reached via hit and walk, while Miguel Rojas also added a hit and a run scored. The Dodgers did not rely on one single inning of lucky contact; they got contributions from several spots in the order and translated them into a comfortable win.
On the mound, Arizona received 4.0 innings from Zac Gallen, who allowed 5 hits and 4 earned runs with 2 walks and 2 strikeouts in the losing effort. J. Morillo and R. Thompson each followed with a scoreless inning, but T. Clarke had a rough outing, allowing 4 earned runs in just one-third of an inning, which effectively broke the game open. A. Hoffmann closed with 1.2 scoreless innings. For Los Angeles, Yoshinobu Yamamoto earned the win by throwing 6.0 innings and allowing 5 hits, 2 earned runs, no walks, and 6 strikeouts. B. Treinen, W. Klein, and T. Scott then combined for 3.0 scoreless innings while allowing only 1 hit. The Dodgers’ staff held Arizona to 2 runs, walked nobody, and struck out 8.
Key takeaway: Los Angeles enters this game with immediate momentum from a convincing opening win in which the lineup showed depth and the pitching staff showed command. Arizona did get one impactful performance from Perdomo, but the broader team output was not enough to keep pace once the Dodgers’ offense got rolling.
Arizona Diamondbacks – Road Form & Team Analysis
The Diamondbacks enter this matchup at 0-1 overall and 0-1 on the road. In their last five games, they recently lost to the Dodgers 8-2, recently lost to Cleveland 10-5, recently lost to Cleveland 7-0, recently won over San Diego 11-1, and recently won over Texas 5-2. That recent run shows a team that had good spring momentum for a stretch but has now dropped three straight games heading into this matchup.
The team stats from Arizona’s most recent game show a lineup that scored 2 runs on 6 hits with 1 home run and no walks. The Diamondbacks struck out 8 times and finished 1-for-3 with runners in scoring position. On the pitching side, Arizona gave up 8 runs on 10 hits, walked 5, and struck out 4. Ryne Nelson’s 2025 profile adds a stronger starting foundation for this contest, as he went 7-3 with a 3.39 ERA and a 1.07 WHIP over 154.0 innings while striking out 132 and allowing only 124 hits.
The key issue for Arizona right now is that the offense has not been broad enough against better competition. Perdomo carried the attack in the opener with a two-run homer, but the rest of the lineup did not bring enough support. The pitching also has to rebound after allowing 8 runs and 10 hits in the previous game. Nelson’s strong 2025 numbers are important here because Arizona needs him to reset the tone after a rough opening loss and give the offense a better platform to work from.
Los Angeles Dodgers – Home Field Breakdown
The Dodgers come into this game at 1-0 overall and 1-0 at home. In their last five games, they recently won over Arizona 8-2, recently lost to the Angels 3-0, recently won over the Angels 13-5, recently tied the Angels 7-7, and recently tied the Athletics 5-5. That recent stretch shows a team that has mixed in some inconsistent spring results but also has the offensive ceiling to take over games when the lineup finds rhythm.
The team stats from Los Angeles’ previous game showed 8 runs on 10 hits with 2 home runs and 5 walks. The Dodgers struck out only 4 times and went 3-for-7 with runners in scoring position. On the mound, Los Angeles allowed 2 runs on 6 hits, issued no walks, and struck out 8. Emmet Sheehan’s 2025 numbers strengthen the pitching outlook for this matchup, as he went 6-3 with a 2.82 ERA and a 0.97 WHIP over 73.1 innings while striking out 89 and allowing just 49 hits.
The Dodgers’ clearest edge is how complete their opener looked. Smith and Pages both delivered home runs and 3 RBI, while Tucker, Betts, Ohtani, Muncy, and Rojas all contributed in different ways. On the mound, Yamamoto and the bullpen combined to allow no walks, which is a strong signal of command and control. When Los Angeles is getting power, patience, and efficient pitching in the same game, it becomes difficult to match up against them for nine innings.
Pitching Matchup Breakdown
This pitching matchup features Arizona right-hander Ryne Nelson, number 19, against Los Angeles right-hander Emmet Sheehan, number 80. Nelson is a right-handed starter who posted a 7-3 record in 2025 with a 3.39 ERA and a 1.07 WHIP over 154.0 innings. He struck out 132 and walked 41 while allowing 124 hits. Opponents hit .217 against him with a .273 opponent on-base percentage and a .381 opponent slugging percentage, producing a .654 opponent OPS. Sheehan is also a right-handed starter, and in 2025 he went 6-3 with a 2.82 ERA and a 0.97 WHIP across 73.1 innings. He struck out 89, walked 22, and allowed 49 hits. Opponents hit just .185 against him with a .251 opponent on-base percentage and a .317 opponent slugging percentage, producing a .568 opponent OPS. Based strictly on the provided data, Sheehan enters with the lower ERA, lower WHIP, and stronger opponent contact suppression numbers, while Nelson brings the larger workload and another solid overall season profile to the mound.
Arizona Diamondbacks vs Los Angeles Dodgers Pick
Arizona Diamondbacks vs Los Angeles Dodgers Spread / Moneyline Pick
The pick in this game is the Los Angeles Dodgers on the moneyline. Los Angeles already won the opener 8-2 and did so with better lineup depth, better situational hitting, and cleaner overall pitching. The Dodgers also enter as the clear favorite in the betting market and hold the edge in the matchup predictor. Sheehan’s 2025 numbers reinforce that position, as he posted a 2.82 ERA and 0.97 WHIP with opponents batting just .185 against him. Nelson had a strong 2025 season as well, but Arizona comes into this game on a three-game losing streak and just gave up 8 runs in the series opener. Based only on the data provided, the Dodgers have the stronger overall profile and are the better side.
Arizona Diamondbacks vs Los Angeles Dodgers Total Pick
I like the over 8.5 in this matchup based strictly on the information provided. The opener between these teams finished with 10 total runs, and Los Angeles showed it can generate offense in bunches with 8 runs on 10 hits and 2 home runs. Arizona has dropped three straight games and has allowed 8 runs and 10 runs in two of those losses, which suggests there is vulnerability on the mound right now. Nelson’s season-long numbers were solid, but the recent team trend points toward scoring opportunities, and I think the Dodgers can help push this game over the posted total.
Final Score Prediction: Los Angeles Dodgers wins 6–4
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