Arizona Diamondbacks vs Milwaukee Brewers Picks and Predictions for Tuesday April 28 2026

By: Kim Smith Published 04/28/2026, 12:45 AM ET
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The Arizona Diamondbacks head to American Family Field in Milwaukee, Wisconsin to take on the Milwaukee Brewers on Tuesday, April 28, 2026, with first pitch scheduled for 7:40 PM and coverage available on MLB.TV. At the time of this writing the odds were not released. This matchup brings together two teams with winning records who are looking to gain an edge in what should be a competitive contest under the lights. For bettors wanting a sharper edge on today’s slate, be sure to explore the latest free MLB picks.

Starting Pitchers Overview

Arizona will turn to Merrill Kelly, who enters with a 1-1 record along with a 9.31 ERA and a 2.28 WHIP over 9.2 innings. He has allowed 15 hits while striking out eight batters and issuing seven walks, along with surrendering four home runs. Milwaukee is set to counter with Chad Patrick, who comes in with a 1-1 record, a 2.35 ERA, and a 1.26 WHIP across 23.0 innings. Patrick has allowed 21 hits while recording 11 strikeouts and eight walks, while giving up two home runs.

Diamondbacks Trying to Stay Competitive on the Road

Arizona enters this matchup with a 15-12 overall record and a balanced 6-6 mark on the road. The Diamondbacks have gone 2-3 in their last five games, recently winning a high-scoring contest while also dropping multiple games in that stretch. They have shown the ability to produce runs but have also struggled to string together consistent results over the past week.

From an offensive standpoint, Arizona is hitting .255 as a team with 132 runs scored and 230 hits. They have hit 27 home runs while posting a .310 on-base percentage and a .426 slugging percentage. On the mound, the Diamondbacks hold a 4.53 ERA and a 1.32 WHIP, allowing opponents to hit .251 against them. Their pitching staff has issued 86 walks and recorded 204 strikeouts.

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One key strength for Arizona has been their offensive production, as indicated by their .255 batting average and .426 slugging percentage. These numbers reflect a lineup capable of generating both consistent contact and power, which can create scoring opportunities even when results have been mixed.

Brewers Looking to Rebound at Home

Milwaukee comes into this game with a 14-13 record and an 8-7 mark at home. The Brewers have gone 1-4 over their last five games, recently picking up a shutout victory but also dropping several contests during that stretch. This recent run shows a team that has struggled to maintain momentum despite flashes of strong performance.

Offensively, Milwaukee is hitting .231 as a team with 132 runs scored and 206 hits. They have hit 19 home runs while posting a .329 on-base percentage and a .349 slugging percentage. On the pitching side, the Brewers have been solid, posting a 3.82 ERA and a 1.30 WHIP while holding opponents to a .237 batting average. Their pitching staff has issued 100 walks and recorded 250 strikeouts.

A notable strength for Milwaukee has been their pitching effectiveness, as shown by their 3.82 ERA and .237 opponent batting average. These numbers indicate that their staff has been able to limit damage and keep games within reach, even when the offense has been inconsistent.

Diamondbacks vs Brewers Picks and Prediction

Diamondbacks vs Brewers Pick

Pick: Brewers Moneyline

Milwaukee appears to have the advantage in this matchup based on the pitching comparison and overall team balance. Chad Patrick has posted a significantly lower ERA and WHIP compared to Merrill Kelly, suggesting better run prevention. Additionally, the Brewers’ pitching staff overall has performed more effectively, limiting opponents to a lower batting average. While Arizona has shown stronger offensive numbers, Milwaukee’s edge on the mound and ability to control games gives them the upper hand in this contest.

Diamondbacks vs Brewers Total Pick

Pick: Over 8.5

I’m leaning toward the over in this matchup due to Arizona’s offensive production and the struggles shown by their starting pitcher. The Diamondbacks have demonstrated the ability to generate runs with a solid batting average and slugging percentage, and their pitching numbers suggest that opponents can also find success at the plate. Even though Milwaukee has strong pitching metrics, the combination of Arizona’s offense and their own recent inconsistency points toward a game with scoring opportunities on both sides.

Final Score Prediction: Brewers 6 – Diamondbacks 5

This prediction was written before the completion of game play on Monday.

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