Arizona Diamondbacks vs Minnesota Twins Picks and Predictions for Friday, September 12, 2025
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Diamondbacks vs Twins Game Information
The Arizona Diamondbacks will be on the road again on Friday for game one of three in Minnesota at Target Field for an 8:10 PM matchup with the Minnesota Twins. Arizona has been mediocre this season, hovering around .500 for much of the year, currently 4th in the National League West. The Minnesota Twins will return home for this series well below .500 this season, currently 20 games back in the American League Central. Stay in the action with our MLB Picks.
Diamondbacks Preview
Geraldo Perdomo has been vital for Arizona this season, leading the team with a .284 batting average and 93 RBI's. Corbin Carroll has been a big piece as well, leading the team with 30 home runs this season. As a unit, Arizona has a .250 batting average and has scored 724 runs on 1242 hits this season.
Twins Preview
Byron Buxton is the offensive leader for Minnesota this season, leading the team with a .275 batting average, 31 home runs, and 76 RBIs. The Minnesota offense has a .239 batting average and has scored 617 runs on 1169 hits. The Minnesota pitching has been shaky last season with a 4.60 team ERA.
Diamondbacks vs Twins Pitching Matchup
Brandon Pfaadt will take the bump for Arizona on Friday with 13 wins and eight losses this season, accompanied by a 5.18 ERA across 153 innings of work. Pablo Lopez will take the mound for Minnesota with five wins and four losses this season and a 2.84 ERA in just over 66 innings of work.
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Diamondbacks vs Twins Free Pick
While a division title is well out of reach, Arizona is just 3.5 games back of a wild-card spot. Look for Arizona to do the work Friday night on the road against a lackluster Minnesota team, leading to the win. Take the Diamondbacks to do the job as they get the win on the road to inch closer to a potential playoff berth.
Pick: Arizona Diamondbacks
Secondary: Over
Lean: Geraldo Perdomo RBI
Final Score Prediction: Arizona Diamondbacks win 7-4.
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